New 'Living Drug' trial targets Tough-to-Treat blood cancers

NCT ID NCT04230265

Summary

This early-stage trial tested a new type of personalized cell therapy for adults with acute myeloid leukemia (AML) that has come back or hasn't responded to other treatments. Doctors modified patients' own immune cells (T-cells) to target a protein called CD123 found on cancer cells. The main goals were to find a safe dose and see if the treatment could help put the cancer into remission.

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Contacts and locations

Locations

  • Erasmus University Medical Center

    Rotterdam, Gelderland, 3015, Netherlands

  • Klinikum der Universität München

    Munich, Bavaria, 81377, Germany

  • Philipps-Universität Marburg

    Marburg, Hesse, 35032, Germany

  • Uniklinik RWTH Aachen

    Aachen, North Rhine-Westphalia, 52074, Germany

  • Universitair Medisch Centrum Groningen

    Groningen, GZ, 9713, Netherlands

  • Universitätsklinikum Dresden

    Dresden, Saxony, 01307, Germany

  • Universitätsklinikum Hamburg-Eppendorf

    Hamburg, 20246, Germany

  • Universitätsklinikum Leipzig

    Leipzig, Saxony, 04103, Germany

  • Universitätsklinikum Ulm

    Ulm, Baden-Wurttemberg, 89081, Germany

  • Universitätsklinikum Würzburg

    Würzburg, Bavaria, 97080, Germany

Conditions

Explore the condition pages connected to this study.