Engineered immune cells target deadly brain cancer in older patients

NCT ID NCT07015242

Recruiting now Disease control Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a personalized immune cell therapy called liso-cel can effectively treat primary central nervous system lymphoma (a rare brain cancer) as the first treatment for patients who are not eligible for stem cell transplants. The trial will enroll 65 adults aged 65+ or with other health conditions to see if this approach can control the cancer longer and improve quality of life. Researchers will track how long patients live without their cancer worsening and measure their response to the treatment.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Phone: •••-•••-•••• Email: •••••@•••••
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Locations

CHU de Rennes - Hopital de Pontchaillou
RECRUITING

Rennes, 35033, France

Contact Phone: •••-•••-••••
Charité - Universitätsmedizin Berlin
RECRUITING

Berlin, 12203, Germany

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Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States

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Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States

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Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States

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Klinikum Chemnitz gGmbH
RECRUITING

Chemnitz, Saxony, 09116, Germany

Contact Phone: •••-•••-••••
Klinikum Stuttgart - Katharinenhospital
RECRUITING

Stuttgart, 70174, Germany

Contact Phone: •••-•••-••••
Local Institution - 0102
NOT_YET_RECRUITING

Paris, 75013, France

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Local Institution - 0103
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Pierre-Bénite, Rhône, 69495, France

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Local Institution - 0104
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Nantes, Loire-Atlantique, 44093 Cedex 1, France

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Local Institution - 0105
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Rouen, 79038, France

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Local Institution - 0106
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Dijon, 21079, France

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Local Institution - 0107
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Montpellier, 34295, France

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Local Institution - 0108
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Pessac, 33600, France

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Local Institution - 0109
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Toulouse, 31059, France

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Local Institution - 0110
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Saint-Cloud, 92210, France

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Local Institution - 0111
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Nice, Alpes-Maritimes, 06202, France

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Local Institution - 0112
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Marseille, 13273, France

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Local Institution - 0113
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Lille, 59037, France

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Local Institution - 0114
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Paris, 75010, France

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Local Institution - 0115
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Strasbourg, 67098, France

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Local Institution - 0116
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Vandœuvre-lès-Nancy, 54500, France

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Local Institution - 0202
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Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany

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Local Institution - 0204
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Cologne, North Rhine-Westphalia, 50937, Germany

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Local Institution - 0206
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Essen, North Rhine-Westphalia, 45147, Germany

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Local Institution - 0207
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Göttingen, 37075, Germany

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Local Institution - 0303
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Houston, Texas, 77030, United States

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Local Institution - 0305
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Aurora, Colorado, 80045, United States

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Local Institution - 0311
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Chicago, Illinois, 60611, United States

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Local Institution - 0315
NOT_YET_RECRUITING

New Brunswick, New Jersey, 08901, United States

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Local Institution - 101
WITHDRAWN

Rennes, 35033, France
Local Institution - 102
WITHDRAWN

Paris, 75013, France
Local Institution - 103
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Pierre-Bénite, 69310, France
Local Institution - 104
WITHDRAWN

Nantes, Loire-Atlantique, 44093 Cedex 1, France
Local Institution - 105
NOT_YET_RECRUITING

Rouen, 79038, France

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Local Institution - 106
NOT_YET_RECRUITING

Dijon, 21079, France

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Local Institution - 107
NOT_YET_RECRUITING

Montpellier, 34295, France

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Local Institution - 108
WITHDRAWN

Pessac, 33600, France
Local Institution - 109
WITHDRAWN

Toulouse, 31059, France
Local Institution - 110
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Saint-Cloud, 92210, France
Local Institution - 111
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Nice, Alpes-Maritimes, 06202, France
Local Institution - 112
NOT_YET_RECRUITING

Marseille, 13273, France

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Local Institution - 113
NOT_YET_RECRUITING

Lille, 59037, France

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Local Institution - 114
NOT_YET_RECRUITING

Paris, 75010, France

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Local Institution - 115
WITHDRAWN

Strasbourg, 67098, France
Local Institution - 116
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Vandœuvre-lès-Nancy, 54500, France
Local Institution - 201
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Stuttgart, 70174, Germany
Local Institution - 202
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Freiburg im Breisgau, 79106, Germany
Local Institution - 203
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Berlin, 12203, Germany
Local Institution - 204
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Cologne, North Rhine-Westphalia, 50937, Germany
Local Institution - 205
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Ulm, Baden-Wurttemberg, 89070, Germany
Local Institution - 206
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Essen, North Rhine-Westphalia, 45147, Germany
Local Institution - 207
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Göttingen, 37075, Germany
Local Institution - 208
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Chemnitz, Saxony, 09116, Germany
Local Institution - 209
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Hamburg, 20246, Germany
Local Institution - 210
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Heidelberg, 69120, Germany
Local Institution - 301
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New York, New York, 10021, United States
Local Institution - 302
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Cleveland, Ohio, 44195, United States
Local Institution - 303
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Houston, Texas, 77030, United States
Local Institution - 304
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Philadelphia, Pennsylvania, 19104, United States
Local Institution - 305
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Aurora, Colorado, 80045, United States
Local Institution - 306
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Seattle, Washington, 98109, United States
Local Institution - 307
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Stanford, California, 94305, United States
Local Institution - 308
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Tampa, Florida, 33612-9416, United States
Local Institution - 309
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Columbus, Ohio, 43202-2224, United States
Local Institution - 310
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Buffalo, New York, 14263, United States
Local Institution - 311
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Chicago, Illinois, 60611, United States
Local Institution - 312
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Nashville, Tennessee, 37203, United States
Local Institution - 313
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Boston, Massachusetts, 02215, United States
Local Institution - 314
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Boston, Massachusetts, 02214, United States
Local Institution - 315
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New Brunswick, New Jersey, 08901, United States
Local Institution - 316
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St Louis, Missouri, 63110-1010, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10021, United States

Contact Phone: •••-•••-••••
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612-9416, United States

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Roswell Park Comprehensive Cancer Center
RECRUITING

Buffalo, New York, 14263, United States

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Sarah Cannon Research Institute Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States

Contact Phone: •••-•••-••••
The Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43202-2224, United States

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University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

Contact Phone: •••-•••-••••
Universitätsklinikum Hamburg-Eppendorf
RECRUITING

Hamburg, 20246, Germany

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Universitätsklinikum Heidelberg
RECRUITING

Heidelberg, 69120, Germany

Contact Phone: •••-•••-••••
Universitätsklinikum Ulm
RECRUITING

Ulm, Baden-Wurttemberg, 89070, Germany

Contact Phone: •••-•••-••••
Washington University School of Medicine in St. Louis
RECRUITING

St Louis, Missouri, 63110-1010, United States

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

LYMPHOMA