Scientists test 'Living Drug' to reset the immune system in devastating autoimmune conditions

NCT ID NCT06152172

Summary

This early-stage study is testing the safety and initial effects of a personalized cell therapy called KYV-101 in adults with severe autoimmune diseases. The therapy involves collecting a patient's own immune cells, modifying them to target harmful B cells, and reinfusing them. Up to 24 participants with conditions like lupus nephritis, scleroderma, and certain muscle or blood vessel diseases will receive one dose and be followed for two years.

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Contacts and locations

Locations

  • Hospital of the Universithy of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.