New CAR-T therapy trial offers hope for severe muscle disease patients

NCT ID NCT06665256

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing a new type of treatment called rapcabtagene autoleucel, a CAR-T cell therapy, for adults with severe inflammatory muscle diseases that haven't responded to other treatments. It will compare this new therapy against a standard treatment option to see which is better at improving muscle strength and reducing symptoms over one year. The main goal is to see if more people achieve significant improvement with the CAR-T therapy.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

FL Medical Clinic Orlando Health
RECRUITING

Zephyrhills, Florida, 33542, United States

Contact

Contact Email: •••••@•••••
LDS Hospital
RECRUITING

Salt Lake City, Utah, 84143, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

Contact

Contact

Contact Email: •••••@•••••

Contact Email: •••••@•••••
Novartis Investigative Site
RECRUITING

Brest, 29200, France
Novartis Investigative Site
SUSPENDED

Lille, 59037, France
Novartis Investigative Site
RECRUITING

Lyon, 69003, France
Novartis Investigative Site
RECRUITING

Paris, 75013, France
Novartis Investigative Site
RECRUITING

Rennes, 35033, France
Novartis Investigative Site
RECRUITING

Cologne, North Rhine-Westphalia, 50937, Germany
Novartis Investigative Site
RECRUITING

Leipzig, Saxony, 04103, Germany
Novartis Investigative Site
RECRUITING

Jena, Thuringia, 07740, Germany
Novartis Investigative Site
RECRUITING

Aachen, 52074, Germany
Novartis Investigative Site
RECRUITING

Hamburg, 20246, Germany
Novartis Investigative Site
RECRUITING

Mainz, 55131, Germany
Novartis Investigative Site
RECRUITING

Nuremberg, 90419, Germany
Novartis Investigative Site
RECRUITING

Ulm, 89081, Germany
Novartis Investigative Site
RECRUITING

Haifa, 3109601, Israel
Novartis Investigative Site
RECRUITING

Ramat Gan, 5265601, Israel
Novartis Investigative Site
RECRUITING

Tel Aviv, 6423906, Israel
Novartis Investigative Site
RECRUITING

Brescia, BS, 25123, Italy
Novartis Investigative Site
RECRUITING

Monza, MB, 20900, Italy
Novartis Investigative Site
RECRUITING

Milan, MI, 20122, Italy
Novartis Investigative Site
RECRUITING

Sapporo, Hokkaido, 0608648, Japan
Novartis Investigative Site
RECRUITING

Kanazawa, Ishikawa-ken, 920 8641, Japan
Novartis Investigative Site
RECRUITING

Yokohama, Kanagawa-ku, 236-0004, Japan
Novartis Investigative Site
RECRUITING

Sendai, Miyagi, 9808574, Japan
Novartis Investigative Site
RECRUITING

Suita, Osaka, 565 0871, Japan
Novartis Investigative Site
RECRUITING

Izumo, Shimane, 693 8501, Japan
Novartis Investigative Site
RECRUITING

Bunkyo-ku, Tokyo, 113-8603, Japan
Novartis Investigative Site
RECRUITING

Bunkyo-ku, Tokyo, 1138519, Japan
Novartis Investigative Site
RECRUITING

Shinjuku-ku, Tokyo, 1608582, Japan
Novartis Investigative Site
RECRUITING

Fukuoka, 8128582, Japan
Novartis Investigative Site
RECRUITING

Kyoto, 6068507, Japan
Novartis Investigative Site
RECRUITING

Amsterdam, North Holland, 1105 AZ, Netherlands
Novartis Investigative Site
RECRUITING

Riyadh, 11211, Saudi Arabia
Novartis Investigative Site
RECRUITING

Singapore, 119074, Singapore
Novartis Investigative Site
RECRUITING

Singapore, 169608, Singapore
Novartis Investigative Site
RECRUITING

Singapore, S308433, Singapore
Novartis Investigative Site
RECRUITING

Santiago Compostela, A Coruna, 15706, Spain
Novartis Investigative Site
RECRUITING

Santander, Cantabria, 39008, Spain
Novartis Investigative Site
RECRUITING

Pamplona, Navarre, 31008, Spain
Novartis Investigative Site
RECRUITING

Barcelona, 08035, Spain
Novartis Investigative Site
RECRUITING

Córdoba, 14004, Spain
Novartis Investigative Site
RECRUITING

Madrid, 28041, Spain
Novartis Investigative Site
RECRUITING

Málaga, 29010, Spain
Novartis Investigative Site
RECRUITING

Salamanca, 37007, Spain
Novartis Investigative Site
RECRUITING

Geneva, 1211, Switzerland
Novartis Investigative Site
RECRUITING

Kaohsiung City, 83301, Taiwan
Novartis Investigative Site
RECRUITING

Taichung, 407219, Taiwan
Novartis Investigative Site
RECRUITING

Taipei, 10002, Taiwan
Novartis Investigative Site
RECRUITING

Sheffield, South Yorkshire, S10 2JF, United Kingdom
Novartis Investigative Site
RECRUITING

London, NW1 2BU, United Kingdom
University Of Alabama
RECRUITING

Birmingham, Alabama, 35294, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
University Of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact

Conditions

Explore the condition pages connected to this study.

IDIOPATHIC INFLAMMATORY MYOPATHIES