New cell therapy trial targets severe lupus when other treatments fail

NCT ID NCT05798117

Summary

This early-stage study is testing a new treatment called YTB323, a type of CAR-T cell therapy, for people with severe lupus that hasn't responded to other strong medications. The main goals are to see if the treatment is safe and if it can reduce lupus disease activity. Researchers will also track how long the modified cells stay in the body and measure their effect on key organs like the kidneys.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Clayton, Victoria, 3168, Australia

  • Novartis Investigative Site

    Paris, 75013, France

  • Novartis Investigative Site

    Pessac, 33604, France

  • Novartis Investigative Site

    Strasbourg, 67091, France

  • Novartis Investigative Site

    Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany

  • Novartis Investigative Site

    Mainz, 55131, Germany

  • Novartis Investigative Site

    Barcelona, 08035, Spain

  • Novartis Investigative Site

    Madrid, 28009, Spain

  • Novartis Investigative Site

    Bern, 3010, Switzerland

  • Novartis Investigative Site

    Lausanne, 1011, Switzerland

Conditions

Explore the condition pages connected to this study.