One-Shot cell therapy aims to reset immune system in Tough-to-Treat lupus

NCT ID NCT07015983

Recruiting now Disease control Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental one-time treatment called CC-97540 for people with active systemic lupus erythematosus (SLE), including lupus affecting the kidneys. The treatment involves collecting and genetically modifying a patient's own immune cells (CAR T-cells) to target and remove the faulty immune cells causing lupus. The main goal is to see if this single infusion can put lupus into remission without needing ongoing steroid or immunosuppressant drugs.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Locations

Atlantic Health System Overlook Medical Center
RECRUITING

Summit, New Jersey, 07901, United States

Contact Phone: •••-•••-••••
Baylor Scott and White Research Institute
RECRUITING

Dallas, Texas, 75246, United States

Contact Phone: •••-•••-••••
CHU Montpellier Lapeyronie Hospital
RECRUITING

Montpellier, Hérault, 34295, France

Contact Phone: •••-•••-••••
Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou
RECRUITING

Rennes, 35033, France

Contact Phone: •••-•••-••••
Charité - Universitaetsmedizin Berlin - Campus Bejnamin Franklin
RECRUITING

Berlin, 10117, Germany

Contact Phone: •••-•••-••••
Chiba University Hospital
RECRUITING

Chiba, 260-8677, Japan

Contact Phone: •••-•••-••••
Cincinnati Children's Hospital Medical Center
RECRUITING

Cincinnati, Ohio, 45229, United States

Contact Phone: •••-•••-••••
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States

Contact Phone: •••-•••-••••
Columbia University Irving Medical Center
RECRUITING

New York, New York, 10032, United States

Contact Phone: •••-•••-••••
Emory University School of Medicine
RECRUITING

Atlanta, Georgia, 30322, United States

Contact Phone: •••-•••-••••
Florida Medical Clinic Orlando Health
RECRUITING

Zephyrhills, Florida, 33542, United States

Contact Phone: •••-•••-••••
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore
RECRUITING

Rome, Lazio, 00168, Italy

Contact Phone: •••-•••-••••
H.R.U Málaga - Hospital General
RECRUITING

Málaga, 29011, Spain

Contact Phone: •••-•••-••••
Hospital Sant Joan de Déu
RECRUITING

Esplugues de Llobregat, Barcelona [Barcelona], 08950, Spain

Contact Phone: •••-•••-••••
Hospital Universitari Vall d'Hebron
RECRUITING

Barcelona, Barcelona [Barcelona], 08035, Spain

Contact Phone: •••-•••-••••
Hospital for Special Surgery
RECRUITING

New York, New York, 10021, United States

Contact Phone: •••-•••-••••
Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10029, United States

Contact Phone: •••-•••-••••
King's College Hospital
RECRUITING

London, London, City of, SE5 9RL, United Kingdom

Contact Phone: •••-•••-••••
Local Institution - 0009
NOT_YET_RECRUITING

Birmingham, Alabama, 35294-3300, United States

Contact
Local Institution - 0010
WITHDRAWN

Chapel Hill, North Carolina, 27599, United States
Local Institution - 0011
WITHDRAWN

Rochester, Minnesota, 55905, United States
Local Institution - 0013
NOT_YET_RECRUITING

Lisbon, Lisbon District, 1649-035, Portugal

Contact
Local Institution - 0016
NOT_YET_RECRUITING

ABB, Buenos Aires F.D., C1199ABB, Argentina

Contact
Local Institution - 0017
WITHDRAWN

ABB, Buenos Aires F.D., C1199ABB, Argentina
Local Institution - 0021
NOT_YET_RECRUITING

São Paulo, São Paulo, 01409-001, Brazil

Contact
Local Institution - 0022
NOT_YET_RECRUITING

São Paulo, 05652-900, Brazil

Contact
Local Institution - 0023
NOT_YET_RECRUITING

Buenos Aires, Buenos Aires F.D., C1118AAT, Argentina

Contact
Local Institution - 0032
NOT_YET_RECRUITING

Milan, Milano, 20162, Italy

Contact
Local Institution - 0034
WITHDRAWN

Lodz, Łódź Voivodeship, 93-513, Poland
Local Institution - 0038
NOT_YET_RECRUITING

Los Angeles, California, 90027, United States

Contact
Local Institution - 0041
WITHDRAWN

Oklahoma City, Oklahoma, 73104, United States
Local Institution - 0042
NOT_YET_RECRUITING

Jerusalem, 9112001, Israel

Contact
Local Institution - 0043
NOT_YET_RECRUITING

Ramat Gan, Central District, 5262100, Israel

Contact
Local Institution - 0044
NOT_YET_RECRUITING

Rome, Roma, 00165, Italy

Contact
Local Institution - 0045
NOT_YET_RECRUITING

Toronto, Ontario, M5G 1X8, Canada

Contact
Local Institution - 0046
WITHDRAWN

Amsterdam, North Holland, 1105 AZ, Netherlands
Local Institution - 0047
NOT_YET_RECRUITING

Copenhagen, 2100, Denmark

Contact
Local Institution - 0048
NOT_YET_RECRUITING

Vancouver, British Columbia, V5Z 1M9, Canada

Contact
Local Institution - 0051
NOT_YET_RECRUITING

Los Angeles, California, 90095, United States

Contact
Local Institution - 0052
NOT_YET_RECRUITING

Boston, Massachusetts, 02215, United States

Contact
Local Institution - 0053
NOT_YET_RECRUITING

Osaka, 545-8586, Japan

Contact
Local Institution - 0054
NOT_YET_RECRUITING

Fukuoka, 812-8582, Japan

Contact
Local Institution - 0055
NOT_YET_RECRUITING

Sapporo, Hokkaido, 0608648, Japan

Contact
Local Institution - 0057
NOT_YET_RECRUITING

London, London, City of, W1T 7HA, United Kingdom

Contact
Local Institution - 0058
NOT_YET_RECRUITING

São Paulo, São Paulo, 01509-010, Brazil

Contact
Local Institution - 0061
WITHDRAWN

London, London, City of, NW1 2PG, United Kingdom
Local Institution - 0063
NOT_YET_RECRUITING

Okayama, 700-8558, Japan

Contact
Local Institution - 0065
NOT_YET_RECRUITING

Charlotte, North Carolina, 28211, United States

Contact
Local Institution - 0068
NOT_YET_RECRUITING

Bunkyo-ku, Tokyo, 113-8431, Japan

Contact
Local Institution - 0069
NOT_YET_RECRUITING

Shinjuku-ku, Tokyo, 1608582, Japan

Contact
Local Institution - 0070
NOT_YET_RECRUITING

Pisa, Tuscany, 56126, Italy

Contact
Local Institution - 0073
NOT_YET_RECRUITING

Orlando, Florida, 32803, United States

Contact
Local Institution - 0074
WITHDRAWN

Honolulu, Hawaii, 96813, United States
Local Institution - 0076
NOT_YET_RECRUITING

Athens, Georgia, 30606, United States

Contact
Local Institution - 0077
NOT_YET_RECRUITING

Córdoba, X5016, Argentina

Contact
Local Institution - 0079
NOT_YET_RECRUITING

Atlanta, Georgia, 30322, United States

Contact
Local Institution - 0080
WITHDRAWN

Scottsdale, Arizona, 85258, United States
Local Institution - 0081
NOT_YET_RECRUITING

Toulouse, Haute-Garonne, 31059, France

Contact
Local Institution - 0082
NOT_YET_RECRUITING

New York, New York, 10016, United States

Contact
Local Institution - 0083
NOT_YET_RECRUITING

Philadelphia, Pennsylvania, 19104, United States

Contact
Local Institution - 0084
NOT_YET_RECRUITING

Herne, 44649, Germany

Contact
Local Institution - 0086
NOT_YET_RECRUITING

Baton Rouge, Louisiana, 70836, United States

Contact
Local Institution - 0087
NOT_YET_RECRUITING

Madrid, 28006, Spain

Contact
Local Institution - 0088
NOT_YET_RECRUITING

Donostia / San Sebastian, Gipuzkoa, 20014, Spain

Contact
Local Institution - 0090
NOT_YET_RECRUITING

Metropolitan Borough of Wirral, Merseyside, L63 4JY, United Kingdom

Contact
Local Institution - 0091
NOT_YET_RECRUITING

Liverpool, L9 7AL, United Kingdom

Contact
Local Institution - 0092
NOT_YET_RECRUITING

Memphis, Tennessee, 38120, United States

Contact
Local Institution - 0093
NOT_YET_RECRUITING

Newport Beach, California, 92658, United States

Contact
Local Institution - 0094
NOT_YET_RECRUITING

Boston, Massachusetts, 02114, United States

Contact
Local Institution - 0095
NOT_YET_RECRUITING

New York, New York, 10032, United States

Contact
Local Institution - 0096
NOT_YET_RECRUITING

Ann Arbor, Michigan, 48109, United States

Contact
Local Institution - 0097
NOT_YET_RECRUITING

Washington D.C., District of Columbia, 20007, United States

Contact
Local Institution - 0098
NOT_YET_RECRUITING

Dallas, Texas, 75390-9068, United States

Contact
Local Institution - 0099
NOT_YET_RECRUITING

Toronto, Ontario, M5T 2S8, Canada

Contact
Local Institution - 0101
NOT_YET_RECRUITING

Manhasset, New York, 11030, United States

Contact
Local Institution - 0102
NOT_YET_RECRUITING

Crownhill, Plymouth, PL6 8DH, United Kingdom

Contact
Local Institution - 0104
NOT_YET_RECRUITING

San Antonio, Texas, 78229, United States

Contact
Local Institution - 0105
NOT_YET_RECRUITING

Denver, Colorado, 80218, United States

Contact
Local Institution - 0106
NOT_YET_RECRUITING

Scottsdale, Arizona, 85259, United States

Contact
Local Institution - 0107
NOT_YET_RECRUITING

Buenos Aires, B1629ODT, Argentina

Contact
Local Institution - 0108
NOT_YET_RECRUITING

Indianapolis, Indiana, 46250, United States

Contact
Lucile Packard Children's Hospital
RECRUITING

Palo Alto, California, 94304, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••
Mayo Clinic in Florida
RECRUITING

Jacksonville, Florida, 32224, United States

Contact Phone: •••-•••-••••
Medizinische Universität Wien
RECRUITING

Vienna, Vienna, 1090, Austria

Contact Phone: •••-•••-••••
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States

Contact Phone: •••-•••-••••
Narodowy Instytut Onkologii - Oddzial w Gliwicach
RECRUITING

Gliwice, Silesian Voivodeship, 44-101, Poland

Contact Phone: •••-•••-••••
Odense Universitetshospital
RECRUITING

Odense, Region Syddanmark, 5000, Denmark

Contact Phone: •••-•••-••••
Pitie Salpetriere University Hospital
RECRUITING

Paris, Île-de-France Region, 75013, France

Contact Phone: •••-•••-••••
Swedish Medical Center
RECRUITING

Seattle, Washington, 98122, United States

Contact Phone: •••-•••-••••
Szpital Specjalistyczny nr 1 w Bytomiu
RECRUITING

Bytom, Silesian Voivodeship, 41-902, Poland

Contact Phone: •••-•••-••••
USF Health
RECRUITING

Tampa, Florida, 33612, United States

Contact Phone: •••-•••-••••
UZ Leuven
RECRUITING

Leuven, Vlaams-Brabant, 3000, Belgium

Contact Phone: •••-•••-••••
Uniklinikum Salzburg
RECRUITING

Salzburg, 5020, Austria

Contact Phone: •••-•••-••••
Universitaetsklinikum Erlangen
RECRUITING

Erlangen, 91054, Germany

Contact Phone: •••-•••-••••
Universitaetsklinikum Koeln
RECRUITING

Cologne, 50937, Germany

Contact Phone: •••-•••-••••
Universitaetsklinikum Magdeburg
RECRUITING

Magdeburg, Saxony-Anhalt, 39120, Germany

Contact Phone: •••-•••-••••
University College London Hospital
RECRUITING

London, London, City of, NW1 2PG, United Kingdom

Contact Phone: •••-•••-••••
University of Colorado Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States

Contact Phone: •••-•••-••••
University of Miami Hospital and Clinics, Sylvester Cancer Center
RECRUITING

Miami, Florida, 33136, United States

Contact Phone: •••-•••-••••
Universitätsklinikum Leipzig
RECRUITING

Leipzig, Saxony, 04103, Germany

Contact Phone: •••-•••-••••
Weill Cornell Medical College
RECRUITING

New York, New York, 10065, United States

Contact
Yokohama City University Hospital
RECRUITING

Yokohama, Kanagawa, 236-0004, Japan

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

LUPUS ERYTHEMATOSUS, SYSTEMIC LUPUS NEPHRITIS