One-Shot gene therapy trial aims to reset immune system in devastating autoimmune diseases

NCT ID NCT07413341

Summary

This early-stage study is testing a new, one-time treatment called TI-0032-III injection for people with severe autoimmune diseases that have not improved with standard medications. The treatment uses a patient's own immune T cells, genetically modified to target and remove harmful B cells that drive the disease. Researchers will first check if the treatment is safe and look for signs it can reduce disease activity in conditions like lupus, Sjögren's syndrome, and scleroderma.

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Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Changzheng Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200003, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.