New CAR-T therapy shows promise for Tough-to-Treat lymphoma

NCT ID NCT05784441

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 22 times

Summary

This early-stage study is testing a new treatment called JNJ-90009530 for adults with B-cell non-Hodgkin lymphoma that has come back or stopped responding to other treatments. The treatment uses a patient's own immune cells, which are modified in a lab to target and attack cancer cells. The main goals are to find a safe dose and to see if the therapy can shrink tumors or slow the disease. About 21 participants will take part in this multicenter trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Austin Hospital

    Heidelberg, 3084, Australia

  • Hadassah Medical Center

    Jerusalem, 9112001, Israel

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • Monash Medical Centre

    Clayton, 3168, Australia

  • Royal Brisbane and Women's Hospital

    Herston, 4029, Australia

  • Royal Prince Alfred Hospital

    Camperdown, 2050, Australia

  • Rutgers University

    New Brunswick, New Jersey, 08901, United States

  • Sheba Medical Center

    Ramat Gan, 5266202, Israel

  • University College London Hospitals

    London, NW1 2BU, United Kingdom

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of Iowa Hospital

    Iowa City, Iowa, 52242, United States

  • University of Kentucky

    Lexington, Kentucky, 40506, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Westmead Hospital

    Westmead, 2145, Australia

Conditions

Explore the condition pages connected to this study.