CAR-T cells take on autoimmune diseases: new hope for RA and Sjögren's patients
NCT ID NCT07048197
First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 26 times
Summary
This early-phase trial tests a personalized cell therapy called rapcabtagene autoleucel in 27 adults with severe rheumatoid arthritis or Sjögren's disease that hasn't improved with standard treatments. The therapy uses a patient's own immune cells, modified to target and calm the overactive immune system. The main goal is to check safety and how long the cells last in the body, with early signs of effectiveness also being explored.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Locations
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Novartis Investigative Site
RECRUITINGBordeaux, 33076, France
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Novartis Investigative Site
RECRUITINGBrest, 29200, France
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Novartis Investigative Site
RECRUITINGLe Kremlin-Bicêtre, 94275, France
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Novartis Investigative Site
RECRUITINGLille, 59037, France
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Novartis Investigative Site
RECRUITINGFreiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
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Novartis Investigative Site
RECRUITINGCologne, North Rhine-Westphalia, 50937, Germany
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Novartis Investigative Site
RECRUITINGBerlin, 13353, Germany
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Novartis Investigative Site
RECRUITINGUlm, 89081, Germany
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Novartis Investigative Site
RECRUITINGSingapore, 119074, Singapore
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Novartis Investigative Site
RECRUITINGBarcelona, 08035, Spain
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Novartis Investigative Site
RECRUITINGMadrid, 28034, Spain
Conditions
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