New study to track brain health after CAR-T cancer treatment

NCT ID NCT07463781

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study follows 100 adults with certain types of lymphoma who are receiving CAR-T cell therapy. Researchers will test memory, attention, and other thinking skills before treatment and at 6, 12, and 24 months after. The goal is to learn how CAR-T therapy affects brain function over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CAR-T cell therapy

What this could lead to

If successful, this could help doctors better understand and manage memory and thinking problems that may occur after CAR-T therapy.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly improve outcomes. Results may not apply to all patients or settings.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma high grade B-cell lymphoma primary mediastinal large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Clinica di Ematologia, AOU Ospedali Riuniti

    Ancona, Italy

    Contact Email: •••••@•••••

  • Divisione di Ematologia - A.O. Ospedali Riuniti Villa Sofia-Cervello

    Palermo, Italy

    Contact Email: •••••@•••••

  • Ematologia - Grande Ospedale Metropolitano Bianchi Melacrino Morelli

    Reggio Calabria, Italy

    Contact Email: •••••@•••••

  • Ematologia - Università Cattolica S. Cuore

    Roma, Italy

    Contact Email: •••••@•••••

  • SC Ematologia - Ospedale "S.G. Moscati"

    Taranto, Italy

    Contact Email: •••••@•••••

  • SCDU Ematologia - AOU SS. Antonio e Biagio e Cesare Arrigo di Alessandria

    Alessandria, Italy

    Contact Email: •••••@•••••

  • SOC Clinica Ematologica - Azienda Sanitaria Universitaria Friuli Centrale (ASU FC)

    Udine, Italy

    Contact Email: •••••@•••••

  • USD-TMO Adulti - ASST Spedali Civili di Brescia

    Brescia, Italy

    Contact Email: •••••@•••••