Engineered immune cells take on lupus in early trial
NCT ID NCT07358988
First seen Jan 24, 2026 · Last updated May 23, 2026 · Updated 13 times
Summary
This early-stage study tests a new treatment called KN5501 for people with moderate to severe lupus that hasn't responded to standard therapies. The treatment uses specially designed immune cells (CAR-NK cells) to target and reduce harmful B cells that drive the disease. The main goals are to check safety and find the right dose, while also seeing if it can lower lupus activity. About 36 adults in China will receive the cell infusion after a short chemotherapy preparation.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Bengbu Medical College First Affiliated Hospital
Bengbu, Anhui, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Changhai Hospital of Shanghai
Shanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Jiangsu Provincial People's Hospital
Nanjing, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Henan University of Science and Technology
Luoyang, Henan, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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