New cancer drug combo tested in advanced tumors

NCT ID NCT05147272

Summary

This early-stage study tested the safety of a new oral drug called RP-6306 when combined with the chemotherapy gemcitabine in adults with advanced solid tumors that had stopped responding to other treatments. The main goal was to find the highest dose patients could tolerate without severe side effects and to see if the combination showed any signs of fighting the cancer. The trial was terminated after enrolling 67 participants.

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Contacts and locations

Locations

  • # 1004, Memorial Sloan Kettering Cancer Institute

    New York, New York, 10065, United States

  • # 1008, Columbia University

    New York, New York, 10032, United States

  • # 1010, University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • # 1016, Mayo Clinic

    Rochester, Minnesota, 55902, United States

  • # 1017, Mayo Clinic

    Jacksonville, Florida, 32224, United States

  • # 1018, Mayo Clinic

    Phoenix, Arizona, 85054, United States

  • # 1019, UCLA, Westwood Cancer Center

    Los Angeles, California, 90095, United States

  • # 1022, Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • # 1023, START Midwest

    Grand Rapids, Michigan, 49546, United States

  • # 2001, Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2C1, Canada

  • # 3003, Sarah Cannon Research Institute

    London, United Kingdom

Conditions

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