New cancer drug duo enters human safety testing
NCT ID NCT06244485
Summary
This early-stage study is testing the safety and initial effectiveness of combining two cancer drugs, valemetostat and a DXd antibody-drug conjugate, in people with advanced solid tumors. It will enroll about 210 adults with specific types of advanced breast, lung, or stomach cancer that have progressed on prior treatments. The main goals are to find a safe dose and see if the combination can shrink tumors.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Aichi Cancer Center Hospital
RECRUITINGNagoya, 464-8681, Japan
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Brcr Medical Center, Inc Dba Boca Raton Clinical Research
RECRUITINGPlantation, Florida, 33322, United States
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City of Hope At Orange County Lennar Foundation Cancer Center
RECRUITINGIrvine, California, 92618, United States
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Clinical Research Alliance
RECRUITINGWestbury, New York, 11590, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Fred Hutchinson Cancer Center
RECRUITINGSeattle, Washington, 98109, United States
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H. Lee Moffitt Cancer Center and Research Institute, Inc
WITHDRAWNTampa, Florida, 33612, United States
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Harbin Medical Univeristy Cancer Hospital
RECRUITINGHeilongjiang, 150081, China
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Hunan Cancer Hospital
RECRUITINGHunan, 410013, China
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IRCCS Istituto Scientifico Romagnolo Per
RECRUITINGCesena, 47014, Italy
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Inova Schar Cancer Institute
WITHDRAWNFairfax, Virginia, 22031, United States
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Jilin Cancer Hospital
RECRUITINGJilin, 130000, China
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Jinana Center Hosptial
RECRUITINGShandong, 240013, China
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Kanagawa Cancer Center
RECRUITINGYokohama, 241-8515, Japan
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Kindai University Hospital
RECRUITINGŌsaka-sayama, 589-8511, Japan
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Mary Crowley Cancer Research Centers
RECRUITINGDallas, Texas, 75230, United States
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Memorial Sloan-Kettering Cancer Center (Mskcc) - New York
RECRUITINGNew York, New York, 10065, United States
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National Cancer Center Hospital
RECRUITINGChūōku, 104-0045, Japan
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National Cancer Center Hospital East
RECRUITINGKashiwa, 277-8577, Japan
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National Hospital Org-Kyushu Cancer Center
RECRUITINGFukuoka, 811-1395, Japan
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Next Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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Osaka International Cancer Institute
RECRUITINGOsaka, 540-0008, Japan
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Osaka University Hospital
RECRUITINGSuita, 565-0871, Japan
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Peking University Third Hospital
RECRUITINGBeijing, 100191, China
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Providence Portland Medical Center
RECRUITINGPortland, Oregon, 97213, United States
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Sharp Memorial Hospital
RECRUITINGSan Diego, California, 92123, United States
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Shizuoka Cancer Center
RECRUITINGShizuoka, 411-8777, Japan
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Sun Yat-Sen University, Cancer Center
RECRUITINGGuangzhou, 510060, China
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SunYat-Sen University Cancer Center
RECRUITINGGuangzhou, 510060, China
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The Cancer Institute Hospital of Jfcr
RECRUITINGKōtoku, 135-8550, Japan
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The Cleveland Clinic Foundation
ACTIVE_NOT_RECRUITINGCleveland, Ohio, 44195, United States
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Unc Hospitals
RECRUITINGChapel Hill, North Carolina, 27514, United States
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University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
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University of Hawaii At Manoa
RECRUITINGHonolulu, Hawaii, 96813, United States
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University of Texas M. D. Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Ut Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
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Valkyrie Clinical Trials
WITHDRAWNLos Angeles, California, 90067, United States
Conditions
Explore the condition pages connected to this study.