New cancer drug duo enters human safety testing

NCT ID NCT06244485

Summary

This early-stage study is testing the safety and initial effectiveness of combining two cancer drugs, valemetostat and a DXd antibody-drug conjugate, in people with advanced solid tumors. It will enroll about 210 adults with specific types of advanced breast, lung, or stomach cancer that have progressed on prior treatments. The main goals are to find a safe dose and see if the combination can shrink tumors.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aichi Cancer Center Hospital

    RECRUITING

    Nagoya, 464-8681, Japan

  • Brcr Medical Center, Inc Dba Boca Raton Clinical Research

    RECRUITING

    Plantation, Florida, 33322, United States

  • City of Hope At Orange County Lennar Foundation Cancer Center

    RECRUITING

    Irvine, California, 92618, United States

  • Clinical Research Alliance

    RECRUITING

    Westbury, New York, 11590, United States

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

  • H. Lee Moffitt Cancer Center and Research Institute, Inc

    WITHDRAWN

    Tampa, Florida, 33612, United States

  • Harbin Medical Univeristy Cancer Hospital

    RECRUITING

    Heilongjiang, 150081, China

  • Hunan Cancer Hospital

    RECRUITING

    Hunan, 410013, China

  • IRCCS Istituto Scientifico Romagnolo Per

    RECRUITING

    Cesena, 47014, Italy

  • Inova Schar Cancer Institute

    WITHDRAWN

    Fairfax, Virginia, 22031, United States

  • Jilin Cancer Hospital

    RECRUITING

    Jilin, 130000, China

  • Jinana Center Hosptial

    RECRUITING

    Shandong, 240013, China

  • Kanagawa Cancer Center

    RECRUITING

    Yokohama, 241-8515, Japan

  • Kindai University Hospital

    RECRUITING

    Ōsaka-sayama, 589-8511, Japan

  • Mary Crowley Cancer Research Centers

    RECRUITING

    Dallas, Texas, 75230, United States

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Sloan-Kettering Cancer Center (Mskcc) - New York

    RECRUITING

    New York, New York, 10065, United States

  • National Cancer Center Hospital

    RECRUITING

    Chūōku, 104-0045, Japan

  • National Cancer Center Hospital East

    RECRUITING

    Kashiwa, 277-8577, Japan

  • National Hospital Org-Kyushu Cancer Center

    RECRUITING

    Fukuoka, 811-1395, Japan

  • Next Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Osaka International Cancer Institute

    RECRUITING

    Osaka, 540-0008, Japan

  • Osaka University Hospital

    RECRUITING

    Suita, 565-0871, Japan

  • Peking University Third Hospital

    RECRUITING

    Beijing, 100191, China

  • Providence Portland Medical Center

    RECRUITING

    Portland, Oregon, 97213, United States

  • Sharp Memorial Hospital

    RECRUITING

    San Diego, California, 92123, United States

  • Shizuoka Cancer Center

    RECRUITING

    Shizuoka, 411-8777, Japan

  • Sun Yat-Sen University, Cancer Center

    RECRUITING

    Guangzhou, 510060, China

  • SunYat-Sen University Cancer Center

    RECRUITING

    Guangzhou, 510060, China

  • The Cancer Institute Hospital of Jfcr

    RECRUITING

    Kōtoku, 135-8550, Japan

  • The Cleveland Clinic Foundation

    ACTIVE_NOT_RECRUITING

    Cleveland, Ohio, 44195, United States

  • Unc Hospitals

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

  • University of Chicago Medical Center

    RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Hawaii At Manoa

    RECRUITING

    Honolulu, Hawaii, 96813, United States

  • University of Texas M. D. Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Ut Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

  • Valkyrie Clinical Trials

    WITHDRAWN

    Los Angeles, California, 90067, United States

Conditions

Explore the condition pages connected to this study.