New drug targets debilitating weight loss in advanced cancer patients

NCT ID NCT05865535

Summary

This early-stage study is testing a new drug called AV-380, given alongside standard chemotherapy, for patients with advanced cancer who are experiencing severe, unintentional weight and muscle loss (cachexia). The main goal is to find a safe dose and see how the body processes the drug. Researchers will enroll about 30 adults who have this specific type of weight loss and high levels of a protein called GDF-15.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advent Health Orlando Hospital

    RECRUITING

    Orlando, Florida, 32804, United States

  • Astera Cancer Care

    RECRUITING

    East Brunswick, New Jersey, 08816, United States

  • Beverly Hills Cancer Center

    RECRUITING

    Beverly Hills, California, 90211, United States

  • Cancer and Blood Specialty Clinic

    RECRUITING

    Lakewood, California, 90712, United States

  • Community Clinical Trials

    RECRUITING

    Kingwood, Texas, 77339, United States

  • Hartford Hospital

    RECRUITING

    Hartford, Connecticut, 06102, United States

  • Hoag Memorial Hospital

    RECRUITING

    Newport Beach, California, 92663, United States

  • MUSC Hollings Cancer Center

    RECRUITING

    Charleston, South Carolina, 29425, United States

  • Nebraska Cancer Specialists

    RECRUITING

    Omaha, Nebraska, 68130, United States

  • New York Cancer And Blood Specialists

    RECRUITING

    Shirley, New York, 11967, United States

  • Oregon Health and Science University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Vanderbilt University Henry-Joyce Cancer Clinic

    RECRUITING

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.