New shot tested to ease agony of sickle cell disease in kids

NCT ID NCT02961218

Summary

This study tested whether monthly injections of a drug called canakinumab could reduce the daily pain and inflammation experienced by children and young adults with sickle cell anemia. For 24 weeks, 49 participants aged 8-20 received either the drug or a placebo (dummy shot) to see if it lowered their pain scores. The study was ended early by the sponsor for strategic reasons not related to safety.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Atlanta, Georgia, 30329, United States

  • Novartis Investigative Site

    Augusta, Georgia, 30912, United States

  • Novartis Investigative Site

    Greenville, North Carolina, 27834, United States

  • Novartis Investigative Site

    Toronto, Ontario, M5G 1X8, Canada

  • Novartis Investigative Site

    Hamburg, 20246, Germany

  • Novartis Investigative Site

    Afula, 1834111, Israel

  • Novartis Investigative Site

    Johannesburg, Guateng, 2193, South Africa

  • Novartis Investigative Site

    Adana, 01330, Turkey (Türkiye)

  • Novartis Investigative Site

    Ankara, 06100, Turkey (Türkiye)

  • Novartis Investigative Site

    Mersin, 33343, Turkey (Türkiye)

  • Novartis Investigative Site

    Wolverhampton, Staffordshire, WS11 5XY, United Kingdom

  • Novartis Investigative Site

    London, E1 1BB, United Kingdom

  • Novartis Investigative Site

    London, NW1 2BU, United Kingdom

  • Novartis Investigative Site

    London, SE1 7EH, United Kingdom

  • Novartis Investigative Site

    London, SE5 9RS, United Kingdom

Conditions

Explore the condition pages connected to this study.