Could a daily antibiotic stop a deadly hospital infection?
NCT ID NCT07221370
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving a daily dose of oral vancomycin can prevent Clostridioides difficile (C. diff) infection in critically ill adults who are already on other antibiotics in the hospital. About 176 high-risk patients will receive either vancomycin or a placebo while they are in the hospital and for a short time after. Researchers will track who develops C. diff and also watch for any rise in antibiotic-resistant bacteria.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vancomycin (an antibiotic taken by mouth)
What this could lead to
If it works, this could give doctors a simple way to prevent dangerous C. diff infections in high-risk hospital patients, reducing illness and deaths.
What could go wrong
This is a mid-stage trial with only 176 participants, so results may not apply to all patients. There is also a risk that using vancomycin could increase antibiotic-resistant bacteria like VRE.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Riverside University Health System
RECRUITINGMoreno Valley, California, 92373, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact