Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a daily antibiotic stop a deadly hospital infection?

NCT ID NCT07221370

Recruiting now Prevention Sponsor: Riverside University Health System Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving a daily dose of oral vancomycin can prevent Clostridioides difficile (C. diff) infection in critically ill adults who are already on other antibiotics in the hospital. About 176 high-risk patients will receive either vancomycin or a placebo while they are in the hospital and for a short time after. Researchers will track who develops C. diff and also watch for any rise in antibiotic-resistant bacteria.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Vancomycin (an antibiotic taken by mouth)
What this could lead to
If it works, this could give doctors a simple way to prevent dangerous C. diff infections in high-risk hospital patients, reducing illness and deaths.
What could go wrong
This is a mid-stage trial with only 176 participants, so results may not apply to all patients. There is also a risk that using vancomycin could increase antibiotic-resistant bacteria like VRE.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CLOSTRIDIUM DIFFICILE INFECTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Clostridium infectious disease Enterococcus infectious disease Clostridium difficile colitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLOSTRIDIUM DIFFICILE INFECTION VANCOMYCIN RESISTANT ENTEROCOCCI INFECTION

Contacts and locations

Locations

  • Riverside University Health System

    RECRUITING

    Moreno Valley, California, 92373, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.