Could a simple warning before anesthesia actually lessen the pain?
NCT ID NCT05886972
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
Propofol, a common anesthesia drug, often causes pain when injected — affecting up to 90% of patients. This trial tests whether simply telling patients beforehand that the injection might hurt can reduce how often and how severely that pain occurs. Researchers will compare pain scores between informed and uninformed female patients aged 20–40 undergoing elective surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- informing patients about possible injection pain before anesthesia
- What this could lead to
- If it works, a simple conversation before anesthesia could reduce pain and anxiety for millions of people undergoing surgery.
- What could go wrong
- This is a small, early-phase trial in healthy young women only. Results may not apply to men, older adults, or people with health conditions. Telling patients about possible pain could also increase anxiety in some people.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mahmoud Hussein Bahr
Beni-suef, Cairo Governorate, 62521, Egypt