Could a common probiotic keep precancerous colon polyps away?

NCT ID NCT07167342

Recruiting now Prevention Sponsor: The Affiliated Hospital of Qingdao University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking a probiotic called Clostridium butyricum can prevent colorectal adenomas (precancerous polyps) from returning after they are removed during a colonoscopy. About 294 adults aged 18-75 who have had all visible polyps removed will take either the probiotic or a placebo daily for up to 3 years. They will have yearly colonoscopies to check for new polyps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Clostridium butyricum (a probiotic bacteria)
What this could lead to: If it works, this could offer a simple, safe way to prevent precancerous colon polyps from returning after removal.
What could go wrong: This is a Phase 4 trial, but probiotics are not proven to prevent polyps. The effect may be small or none, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL ADENOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

colorectal adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL ADENOMA PROBIOTICS

Contacts and locations

Locations

Weifang People's Hospital
RECRUITING

Weifang, Shandong, China
the Affiliated Hospital of QIngdao University
RECRUITING

Qingdao, Shandong, 266000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.