Could a common probiotic keep precancerous colon polyps away?

NCT ID NCT07167342

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking a probiotic called Clostridium butyricum can prevent colorectal adenomas (precancerous polyps) from returning after they are removed during a colonoscopy. About 294 adults aged 18-75 who have had all visible polyps removed will take either the probiotic or a placebo daily for up to 3 years. They will have yearly colonoscopies to check for new polyps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Clostridium butyricum (a probiotic bacteria)

What this could lead to

If it works, this could offer a simple, safe way to prevent precancerous colon polyps from returning after removal.

What could go wrong

This is a Phase 4 trial, but probiotics are not proven to prevent polyps. The effect may be small or none, and results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Weifang People's Hospital

    RECRUITING

    Weifang, Shandong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • the Affiliated Hospital of QIngdao University

    RECRUITING

    Qingdao, Shandong, 266000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••