Did two years of eating less slow aging? scientists revisit CALERIE participants
NCT ID NCT05651620
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study checks in on people who took part in a major calorie restriction trial over a decade ago. Researchers want to see if the two-year diet change left any lasting effects on biological age and overall health. About 216 former participants will have their health measured to look for long-term benefits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- calorie restriction
- What this could lead to
- If successful, this could show that a period of calorie restriction has lasting benefits on aging and health, potentially guiding future anti-aging strategies.
- What could go wrong
- This is an observational follow-up, not a new treatment trial. Results may be limited by the original study's size and participant characteristics, and cannot prove cause and effect.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CALORIE RESTRICTION are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University
Boston, Massachusetts, 02111, United States
-
Pennington Biomedical Research Center
Baton Rouge, Louisiana, 70808, United States
-
Washington University School of Medicine
St Louis, Missouri, 63110-1010, United States