Could a simple calcium injection prevent dangerous bleeding in C-Sections?

NCT ID NCT06235749

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This trial investigates whether giving calcium gluconate intravenously after umbilical cord clamping can reduce blood loss during elective cesarean deliveries. Calcium is essential for blood clotting and uterine muscle contraction, and low calcium levels are linked to heavier bleeding. The study will compare hemoglobin drop and bleeding complications between women who receive calcium gluconate and those who receive a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
calcium gluconate 10% solution given intravenously after umbilical cord clamping
What this could lead to
If effective, this simple, low-cost intervention could become a standard preventive measure to reduce dangerous bleeding during cesarean deliveries.
What could go wrong
This is a single-center trial, and calcium's effect on bleeding in this setting is not yet proven. The benefit may be small or absent, and rare side effects like hypercalcemia or arrhythmia are possible.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Edith Wolfson Medical Center

    RECRUITING

    Holon, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rambam Medical Center

    RECRUITING

    Haifa, 3525408, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Shamir Medical Center

    RECRUITING

    Be’er Ya‘aqov, Israel

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Soroka Medical Center

    RECRUITING

    Beersheba, Israel

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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