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New combo shot helps east asians shed pounds in major trial

NCT ID NCT05813925

Completed Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

First seen Jan 28, 2026 · Last updated May 16, 2026 · Updated 21 times

Summary

This study tested a new weekly injection called CagriSema (a mix of two medicines) in 331 East Asian adults with overweight or obesity. Participants received the shot for about 1.5 years to see how much weight they lost compared to those taking semaglutide alone. The goal was to measure percentage of body weight lost and other health improvements.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Akaicho Clinic

    Chiba-shi, Chiba, 260-0804, Japan

  • Fukuwa Clinic

    Tokyo, 104-0031, Japan

  • Fukuwa Clinic_Internal Medicine

    Tokyo, 104-0031, Japan

  • Heiwadai Hospital_Internal Medicine

    Miyazaki, Miyazaki, 880-0034, Japan

  • Iwate Medical University Uchimaru Medical Center, Division of Diabetes and Metabolism and Endocrine medicine

    Numakunai, 020-8505, Japan

  • Kawada Clinic

    Gunma, 373-0036, Japan

  • Minamino Cardiovascular Hospital_Cardiovascular medicine

    Tokyo, 192-0918, Japan

  • Naka Kinen Clinic

    Ibaraki, 311-0113, Japan

  • Naka Kinen Clinic_Internal medicine

    Ibaraki, 311-0113, Japan

  • National Taiwan University Hospital_main

    Taipei, 100, Taiwan

  • OCROM Clinic_Internal medicine

    Suita-shi, Osaka, 565-0853, Japan

  • Okabe Clinic

    Chuo-ku, Tokyo, 104-0061, Japan

  • Osaka NISHI-UMEDA Clinic

    Osaka, 530-0001, Japan

  • Osaka NISHI-UMEDA Clinic_Internal Medicine

    Osaka, 530-0001, Japan

  • Seino Internal Medicine Clinic_Internal medicine

    Koriyama-shi, Fukushima, Fukushima, Japan, 963-8851, Japan

  • Shinden Higashi Clinic

    Sendai-shi, Miyagi, 983-0039, Japan

  • Shinden Higashi Clinic_Internal medicine

    Sendai-shi, Miyagi, 983-0039, Japan

  • Shinsapporo Seiryou Hospital, General Clinical Department

    Sapporo-shi, Hokkaido, 004-0004, Japan

  • Suidoubashi Medical Clinic_Internal Medicine

    Chiyoda-ku, Tokyo, 101-0065, Japan

  • TOSAKI Clinic for Diabetes and Endocrinology_Diabetes and Endocrinology

    Aichi, 468-0009, Japan

  • The Institute of Medical Science, Asahi Life Foundation

    Chuo-ku, Tokyo, 103-0002, Japan

  • The Institute of Medical Science, Asahi Life Foundation_Internal Medicine

    Chuo-ku, Tokyo, 103-0002, Japan

  • The University of Tokyo Hospital, Diabetes and Metabolic

    Bunkyo-ku, Tokyo, 113-8655, Japan

  • ToCROM Clinic_Internal Medicine

    Tokyo, 160-0008, Japan

  • Tokyo-Eki Center-building Clinic_Internal Medicine

    Tokyo, 103-0027, Japan

  • Tsuruma Kaneshiro Diabetes Clinic

    Yamato-shi, Kanagawa, 242-0004, Japan

  • Tsuruma Kaneshiro Diabetes Clinic_Internal medicine

    Yamato-shi, Kanagawa, 242-0004, Japan

  • Yao Tokushukai General Hospital_Cardiovascular division

    Yao-shi, Osaka, 581-0011, Japan

Conditions

Explore the condition pages connected to this study.

OBESITY OR OVERWEIGHT