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Coffee's hidden power: could your morning cup boost blood stem cells?

NCT ID NCT07193264

Knowledge-focused Sponsor: Jasmin Rettkowski Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study looks at how caffeine, the stimulant in coffee and energy drinks, affects blood stem cells in healthy adults. Researchers will compare people who drink caffeine regularly with those who rarely do. All participants will take a single 200 mg caffeine tablet (about one cup of coffee) on an empty stomach, and blood samples will be taken before and three hours after to see if caffeine changes how stem cells move from bone marrow into the blood.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
caffeine (200 mg tablet)
What this could lead to
If successful, this could reveal how caffeine influences blood stem cell activity, potentially informing future therapies for blood disorders.
What could go wrong
This is a small, early-stage observational study in healthy adults, not a treatment trial. Results may not apply to people with illnesses or lead to direct medical benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Able to give consent. * Healthy adults aged ≥ 18 years. * Regular caffeine consumers (≥1 coffee cup/day or ≥1 energy drink/day) or non-consumers (≤1 cup/month and ≤1 energy drink/month) for at least 6 months. * Willingness to comply with fasting requirements and study procedures. Exclusion Criteria: * Chronic illnesses or medication use affecting metabolism, including metabolic disorders (e.g., diabetes, thyroid dysfunction, metabolic syndrome). * Personal history of cancer. * Personal history of hematological disorders. * History of radiation therapy. * Known caffeine hypersensitivity or intolerance. * Known immunosuppression.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy adults; hematopoietic system; caffeine

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • ETH GLC

    NOT_YET_RECRUITING

    Zurich, Canton of Zurich, 8006, Switzerland

  • ETH GLC

    RECRUITING

    Zurich, Canton of Zurich, 8006, Switzerland