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Custom 3D-Printed retainers could outlast standard wires after braces

NCT ID NCT06529601

Disease control Sponsor: Azienda Ospedaliero-Universitaria Careggi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study compares two types of fixed retainers used after braces to keep teeth aligned: a custom-made CAD/CAM retainer (Keeppy) and a standard braided wire retainer. Researchers want to see which one breaks or detaches less often over 6 months and 2 years, and which one keeps gums healthier. The trial involves 54 people aged 13 to 20 who have just finished orthodontic treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
CAD/CAM mandibular fixed retainer (Keeppy)
What this could lead to
If successful, this could show that custom-made retainers are more durable and better for gum health than standard wire retainers, improving long-term orthodontic outcomes.
What could go wrong
This is a small, single-center trial with only 54 participants, so results may not apply to everyone. The custom retainer may not prove superior or could have unexpected issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 54 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2025

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

13 to 20 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who have completed fixed orthodontic therapy between the ages of 13 and 20 years; * Patients whose parents will sign the informed consent Exclusion Criteria: * Presence of dental anomalies in number (excess or deficiency) in the lower anterior teeth * Patients with metal allergies.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Orthodontic retainers

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Orthodontic Clinic, Division of Dentistry, Careggi University Hospital

    RECRUITING

    Florence, Italy

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