Major trial aims to shield seniors from dangerous gut infection

NCT ID NCT07282665

Recruiting now ⭐️ VACCINE ⭐️ Sponsor: Pfizer Source: ClinicalTrials.gov ↗

Summary

This large study is testing whether a new vaccine can prevent C. difficile infections, a serious cause of diarrhea, in adults aged 65 and older. About 32,000 participants will receive either the real vaccine or a placebo (saltwater) shot and be followed for up to 3.5 years. The main goal is to see if the vaccine safely reduces the number of C. diff infections compared to the placebo.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AMR Clinical
RECRUITING

Newton, Kansas, 67114, United States
Accellacare - Cary
RECRUITING

Cary, North Carolina, 27518, United States
Accellacare - Hickory
RECRUITING

Hickory, North Carolina, 28601, United States
Accellacare - McFarland
RECRUITING

Ames, Iowa, 50010, United States
Accellacare - Raleigh
RECRUITING

Raleigh, North Carolina, 27609, United States
Accellacare - Salisbury
RECRUITING

Salisbury, North Carolina, 28144, United States
Accellacare - Wilmington
RECRUITING

Wilmington, North Carolina, 28401, United States
Accellacare - Winston-Salem
NOT_YET_RECRUITING

Winston-Salem, North Carolina, 27103, United States
Albuquerque Clinical Trials, Inc.
RECRUITING

Albuquerque, New Mexico, 87102, United States
Angels Clinical Research Institute
RECRUITING

Tampa, Florida, 33614, United States
Applied Research Center of Arkansas
RECRUITING

Little Rock, Arkansas, 72205, United States
Brunel Medical Practice (St Marychurch)
NOT_YET_RECRUITING

Torquay, Devon, TQ1 4QX, United Kingdom
CDC Centro Médico
NOT_YET_RECRUITING

Luján de Cuyo, Mendoza Province, 5507, Argentina
CTI Clinical Research Center
RECRUITING

Cincinnati, Ohio, 45212, United States
Capital Area Research, LLC
RECRUITING

Camp Hill, Pennsylvania, 17011, United States
Carbon Health - San Mateo - Hillsdale Mall
RECRUITING

San Mateo, California, 94403, United States
Care Research Inc
RECRUITING

Miami, Florida, 33130, United States
Cedar Health Research - Euless
NOT_YET_RECRUITING

Euless, Texas, 76040, United States
Centricity Research Columbus Georgia Multispecialty
RECRUITING

Columbus, Georgia, 31904, United States
Centro Medico Barrio Parque
NOT_YET_RECRUITING

Buenos Aires, 1425, Argentina
Charisma Medical and Research Center
RECRUITING

Miami Lakes, Florida, 33014, United States
Cheadle Community Hospital
NOT_YET_RECRUITING

Cheadle, Staffordshire, ST10 1NS, United Kingdom
Clinica Privada del Sol S.A
NOT_YET_RECRUITING

Córdoba, Córdoba Province, X5000IIH, Argentina
Clinical Neuroscience Solutions Inc.
RECRUITING

Memphis, Tennessee, 38119, United States
Clinical Neuroscience Solutions, Inc. dba CNS Healthcare
RECRUITING

Jacksonville, Florida, 32256, United States
Clinical Research Partners, LLC
NOT_YET_RECRUITING

Richmond, Virginia, 23226, United States
Columbia University Irving Medical Center
NOT_YET_RECRUITING

New York, New York, 10032, United States
DM Clinical Research - Chicago
RECRUITING

Melrose Park, Illinois, 60160, United States
DM Clinical Research - Detroit
RECRUITING

Southfield, Michigan, 48076, United States
DM Clinical Research - Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
DM Clinical Research- Cyfair
RECRUITING

Houston, Texas, 77065, United States
Diablo Clinical Research, Inc.
RECRUITING

Walnut Creek, California, 94598, United States
Duke University Health System
NOT_YET_RECRUITING

Raleigh, North Carolina, 27609, United States
Duke Vaccine and Trials Unit
NOT_YET_RECRUITING

Durham, North Carolina, 27703, United States
Dynamed Clinical Research, LP d/b/a DM Clinical Research
RECRUITING

Tomball, Texas, 77375, United States
Emory Steiner Building Research Center
NOT_YET_RECRUITING

Atlanta, Georgia, 30303, United States
Emory University Woodruff Extension Building (WEB)
NOT_YET_RECRUITING

Atlanta, Georgia, 30303, United States
Entrust Clinical Research
RECRUITING

Miami, Florida, 33176, United States
Epic Medical Research-Sun City
RECRUITING

Sun City, Arizona, 85351, United States
Equipo Ciencia
RECRUITING

Buenos Aires, Buenos Aires F.D., C1428BNF, Argentina
Family Health Watch - KeyPoint Clinical Research
RECRUITING

Dallas, Texas, 75237, United States
Fundación Huésped
NOT_YET_RECRUITING

Buenos Aires, Buenos Aires F.D., 1427, Argentina
GW Vaccine Research Unit
NOT_YET_RECRUITING

Washington D.C., District of Columbia, 20037, United States
Icahn School of Medicine at Mount Sinai
NOT_YET_RECRUITING

New York, New York, 10029, United States
Indago Research & Health Center, Inc
RECRUITING

Hialeah, Florida, 33012, United States
Innovation Medical Research Center
NOT_YET_RECRUITING

Palmetto Bay, Florida, 33157, United States
J. Lewis Research, Inc. / Foothill Family Clinic South
RECRUITING

Salt Lake City, Utah, 84121, United States
Kaiser Permanente - San Diego Medical Center
NOT_YET_RECRUITING

San Diego, California, 92123, United States
Kaiser Permanente Center for Health Research
RECRUITING

Portland, Oregon, 97227, United States
Kaiser Permanente Daly City
NOT_YET_RECRUITING

Daly City, California, 94015, United States
Kaiser Permanente Los Angeles Medical Center
NOT_YET_RECRUITING

Los Angeles, California, 90027, United States
Kaiser Permanente Oakland
NOT_YET_RECRUITING

Oakland, California, 94611, United States
Kaiser Permanente Oncology Pharmacy #014C
NOT_YET_RECRUITING

Los Angeles, California, 90027, United States
Kaiser Permanente Ontario Medical Center
NOT_YET_RECRUITING

Ontario, California, 91761, United States
Kaiser Permanente Roseville
NOT_YET_RECRUITING

Roseville, California, 95661, United States
Kaiser Permanente Sacramento
NOT_YET_RECRUITING

Sacramento, California, 95815, United States
Kaiser Permanente San Jose
NOT_YET_RECRUITING

San Jose, California, 95119, United States
Kaiser Permanente Santa Clara
NOT_YET_RECRUITING

Santa Clara, California, 95051, United States
Kaiser Permanente South Sacramento
NOT_YET_RECRUITING

Sacramento, California, 95823, United States
Kaiser Permanente Viewridge Medical Office
NOT_YET_RECRUITING

San Diego, California, 92123, United States
Kaiser Permanente Walnut Creek
NOT_YET_RECRUITING

Walnut Creek, California, 94596, United States
KeyPoint Clinical Research
RECRUITING

Dallas, Texas, 75240, United States
Knowle House Surgery
NOT_YET_RECRUITING

Plymouth, Devon, PL5 3JB, United Kingdom
Lakeside Surgery
NOT_YET_RECRUITING

Corby, Northamptonshire, NN17 2UR, United Kingdom
Lakeview Clinical Research
RECRUITING

Guntersville, Alabama, 35976, United States
Layton Medical Centre
NOT_YET_RECRUITING

Blackpool, Lancashire, FY3 7EN, United Kingdom
M3 Wake Research - Lake City
RECRUITING

Lake City, Florida, 32055, United States
Manchester Royal Infirmary
NOT_YET_RECRUITING

Manchester, M13 9WU, United Kingdom
McFarland Clinic, PC
RECRUITING

Ames, Iowa, 50010, United States
Med Partners, Inc. dba Premiere Medical Center of Burbank, Inc.
RECRUITING

Toluca Lake, California, 91602, United States
Medical Affiliated Research Center
RECRUITING

Huntsville, Alabama, 35801, United States
Medication Management
NOT_YET_RECRUITING

Greensboro, North Carolina, 27405, United States
Mercury Clinical Research - Santa Clara Family Clinic
RECRUITING

Houston, Texas, 77087, United States
Montefiore Medical Center
NOT_YET_RECRUITING

The Bronx, New York, 10467, United States
Mount Sinai Morningside
NOT_YET_RECRUITING

New York, New York, 10025, United States
Mount Sinai Queens
NOT_YET_RECRUITING

Long Island City, New York, 11102, United States
Mount Sinai West
NOT_YET_RECRUITING

New York, New York, 10019, United States
NYU Langone Health
NOT_YET_RECRUITING

Brooklyn, New York, 11220, United States
NYU Langone Health
NOT_YET_RECRUITING

Mineola, New York, 11501, United States
NYU Langone Health
NOT_YET_RECRUITING

New York, New York, 10016, United States
New Phase Research and Development
RECRUITING

Knoxville, Tennessee, 37909, United States
Newquay Health Centre
NOT_YET_RECRUITING

Newquay, Cornwall, TR7 1RU, United Kingdom
North Alabama Research Center
RECRUITING

Athens, Alabama, 35611, United States
North Shore University Hospital
NOT_YET_RECRUITING

Manhasset, New York, 11030, United States
North Texas Infectious Diseases Consultants, P.A
NOT_YET_RECRUITING

Dallas, Texas, 75246, United States
North Wales Clinical Research Facility
NOT_YET_RECRUITING

Wrexham, Wrexham [wrecsam Gb-wrc], LL13 7YP, United Kingdom
Northern Westchester Hospital
NOT_YET_RECRUITING

Mount Kisco, New York, 10549, United States
Northwell Health Infectious Disease
NOT_YET_RECRUITING

Manhasset, New York, 11030, United States
Northwest Houston Heart Center
RECRUITING

Tomball, Texas, 77375, United States
Ormeau Clinical Trials
RECRUITING

Belfast, Northern Ireland, BT2 8BG, United Kingdom
Palm Springs Community Health Center
NOT_YET_RECRUITING

Miami Lakes, Florida, 33014, United States
Panthera Biopartners - Glasgow
RECRUITING

Glasgow, Scotland, G51 4TY, United Kingdom
Panthera Biopartners - Manchester
RECRUITING

Rochdale, Manchester, OL11 4AU, United Kingdom
Panthera Biopartners - Preston
RECRUITING

Preston, England, PR2 9QB, United Kingdom
Panthera Biopartners - Sheffield
NOT_YET_RECRUITING

Sheffield, S2 5FX, United Kingdom
Panthera Clinic - York
RECRUITING

York, North Yorkshire, YO24 4LJ, United Kingdom
Phelps Hospital Geriatric Medicine & Improvement Science
NOT_YET_RECRUITING

Sleepy Hollow, New York, 10591, United States
Proactive Clinical Research,LLC
RECRUITING

Fort Lauderdale, Florida, 33308, United States
Renown Center for Advanced Medicine
RECRUITING

Reno, Nevada, 89502, United States
Renown Regional Medical Center
RECRUITING

Reno, Nevada, 89502, United States
Revive Research Institute, Inc.
RECRUITING

Southfield, Michigan, 48075, United States
Rochester Clinical Research, LLC
RECRUITING

Rochester, New York, 14609, United States
Royal Devon & Exeter Hospital
NOT_YET_RECRUITING

Exeter, Devon, EX2 5DW, United Kingdom
Rutgers Robert Wood Johnson Medical School
NOT_YET_RECRUITING

New Brunswick, New Jersey, 08901, United States
Sanatorio Sagrado Corazón
NOT_YET_RECRUITING

Buenos Aires, 1039, Argentina
South Florida Research Organization
RECRUITING

Medley, Florida, 33166, United States
South Jersey Infectious Disease
RECRUITING

Somers Point, New Jersey, 08244, United States
Southampton General Hospital
NOT_YET_RECRUITING

Southampton, Hampshire, SO16 6YD, United Kingdom
Sundance Clinical Research
RECRUITING

St Louis, Missouri, 63141, United States
Synexus Manchester Clinical Research Centre
RECRUITING

Manchester, M15 6SE, United Kingdom
Synexus Midlands Clinical Research Centre
NOT_YET_RECRUITING

Birmingham, WEST Midlands, B15 2SQ, United Kingdom
Synexus Scotland Clinical Research Centre
NOT_YET_RECRUITING

Glasgow, Glasgow CITY, ML4 3NJ, United Kingdom
The GW Medical Faculty Associates
NOT_YET_RECRUITING

Washington D.C., District of Columbia, 20037, United States
The Hope Clinic of Emory University
RECRUITING

Decatur, Georgia, 30030, United States
Trial Management Associates
RECRUITING

Myrtle Beach, South Carolina, 29572, United States
Trial Management Associates, LLC
RECRUITING

Myrtle Beach, South Carolina, 29572, United States
University Health
RECRUITING

Reno, Nevada, 89519, United States
University of Washington - Harborview Medical Center
RECRUITING

Seattle, Washington, 98104, United States
Upstate Global Health Institute
RECRUITING

East Syracuse, New York, 13057, United States
Velocity Clinical Research, Grand Island
RECRUITING

Grand Island, Nebraska, 68803, United States
Velocity Clinical Research, Omaha
NOT_YET_RECRUITING

Omaha, Nebraska, 68134, United States
Velocity Clinical Research, San Bernardino
RECRUITING

San Bernardino, California, 92408, United States
Velocity Clinical Research, Savannah
RECRUITING

Savannah, Georgia, 31406, United States
Velocity Clinical Research, Sioux City
RECRUITING

Sioux City, Iowa, 51106, United States
Velocity Clinical Research, Spartanburg
NOT_YET_RECRUITING

Spartanburg, South Carolina, 29303, United States
Wake Forest Baptist Health
NOT_YET_RECRUITING

Winston-Salem, North Carolina, 27157, United States
Wake Forest University Health Science
NOT_YET_RECRUITING

High Point, North Carolina, 27262, United States
Walker Family Care
RECRUITING

Little River, South Carolina, 29566, United States
Washington University School of Medicine
NOT_YET_RECRUITING

St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.

CLOSTRIDIOIDES DIFFICILE ASSOCIATED DISEASE