C. diff mystery: new study aims to unlock why infections keep coming back

NCT ID NCT06030245

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 100 hospitalized patients with Clostridioides difficile infection to track how quickly the bacteria clears from the gut during and after standard antibiotic treatment. Researchers will also analyze gut bacteria and immune responses in stool samples to identify factors linked to recurrence. The goal is to improve prevention and treatment strategies for this often-recurring infection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could identify factors that predict or prevent C. diff recurrence, leading to improved treatment guidelines and reduced relapse rates.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may not lead to immediate changes in patient care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Clostridium difficile colitis Clostridium infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fondation Hôpital Saint-Joseph

    RECRUITING

    Paris, 75014, France

    Contact