C. diff mystery: new study aims to unlock why infections keep coming back
NCT ID NCT06030245
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 100 hospitalized patients with Clostridioides difficile infection to track how quickly the bacteria clears from the gut during and after standard antibiotic treatment. Researchers will also analyze gut bacteria and immune responses in stool samples to identify factors linked to recurrence. The goal is to improve prevention and treatment strategies for this often-recurring infection.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could identify factors that predict or prevent C. diff recurrence, leading to improved treatment guidelines and reduced relapse rates.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may not lead to immediate changes in patient care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fondation Hôpital Saint-Joseph
RECRUITINGParis, 75014, France
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