Leg artery showdown: bypass vs. balloon for blockages

NCT ID NCT05216731

Recruiting now Disease control Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two treatments for long blockages (15-25 cm) in the leg's main artery. One is bypass surgery, which uses a vein or artificial tube to reroute blood flow. The other is a less invasive procedure using a balloon to open the artery, often with a stent. The trial will enroll 290 adults with leg pain when walking (claudication) to see which treatment keeps the artery open longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If this trial succeeds, it could show which treatment (bypass surgery or a less invasive procedure) works better for keeping leg arteries open in people with long blockages.
What could go wrong: This is a mid-stage trial with 290 people, so results may not apply to everyone. Both procedures have risks like infection, bleeding, or the artery re-blocking.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

femoral neuropathy peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LESION; FEMORAL

Contacts and locations

Locations

CHU - Hôpitaux de Bordeaux
ACTIVE_NOT_RECRUITING

Bordeaux, 33 000, France
CHU Carémeau
NOT_YET_RECRUITING

Nîmes, 30 029, France
CHU de Nice
ACTIVE_NOT_RECRUITING

Nice, 06 001, France
CHU de Poitiers
RECRUITING

Poitiers, 86 000, France
CHU de Rangueil
ACTIVE_NOT_RECRUITING

Toulouse, 31 400, France
Centre hospitalier René Dubos
ACTIVE_NOT_RECRUITING

Cergy-Pontoise, 95 300, France
Hôpital Ambroise Paré, APHP
ACTIVE_NOT_RECRUITING

Boulogne-Billancourt, 92 100, France
Hôpital Bichat - Claude Bernard, APHP
ACTIVE_NOT_RECRUITING

Paris, 75 018, France
Hôpital Edouard Herriot
ACTIVE_NOT_RECRUITING

Lyon, 69 003, France
Hôpital Européen Georges Pompidou, APHP
ACTIVE_NOT_RECRUITING

Paris, 75 015, France
Hôpital François Mitterrand
RECRUITING

Dijon, 21 000, France
Hôpital Henri Mondor, APHP
RECRUITING

Créteil, 94 010, France
Hôpital La Pitié-Salpêtrière, APHP
NOT_YET_RECRUITING

Paris, 75013, France
Hôpital de la Cavale Blanche
ACTIVE_NOT_RECRUITING

Brest, 29 200, France
Hôpital de la Timone, APHP
NOT_YET_RECRUITING

Marseille, 13 005, France
Institut Lorrain du Cœur et des Vaisseaux Louis Mathieu
NOT_YET_RECRUITING

Vandœuvre-lès-Nancy, 54 511, France