New antibody drug tested for hard-to-treat cancers

NCT ID NCT06932952

First seen Jan 17, 2026 · Last updated Apr 28, 2026 · Updated 9 times

Summary

This early-phase trial tests a new drug called BYON4228, alone or with another drug (pembrolizumab), in people with advanced solid tumors that have not responded to standard treatments. The study aims to find a safe dose and see if the drug can shrink tumors. Only 7 participants are enrolled, so results are very preliminary.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CIOCC Hospital Universitario HM Sanchinarro

    Madrid, Spain

  • Hospital Universitario Fundación Jiménez Díaz

    Madrid, Spain

  • Institut Jules Bordet

    Brussels, Belgium

  • The Christie NHS Foundation Trust

    Manchester, United Kingdom

  • The Royal Marsden

    Sutton, United Kingdom

  • UZ Leuven

    Leuven, Belgium

Conditions

Explore the condition pages connected to this study.