New hope for HAE patients: experimental drug aims to slash attack rate

NCT ID NCT06846398

First seen Mar 12, 2026 · Last updated Apr 30, 2026 · Updated 9 times

Summary

This study tests an experimental drug called BW-20805 in 25 adults with hereditary angioedema (HAE), a condition that causes sudden, painful swelling attacks. The goal is to see if the drug can reduce how often these attacks happen over 24 weeks. Participants will receive the drug and be monitored for safety and effectiveness for up to 96 weeks.

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Contacts and locations

Locations

  • Azienda Ospedale - Universita di Padova

    Padova, PD, 35128, Italy

  • Azienda Ospedaliero Universitaria Policlinico G. Rodolico San Marco - Ospedale San Marco

    Catania, Catania, 95125, Italy

  • Azienda Ospedaliero-Universitaria Careggi

    Florence, Florence, 50134, Italy

  • Charité - Universitätsmedizin Berlin

    Berlin, State of Berlin, 12200, Germany

  • Duke University Medicine Center

    Durham, North Carolina, 27705, United States

  • First Affiliated Hospital of Kunming Medical University

    Kunming, Yunnan, 650032, China

  • Hospital Universitario Virgen del Rocío

    Seville, Sevilla, 41013, Spain

  • Inova Clinical Trials and Research Center

    Falls Church, Virginia, 22031, United States

  • Institute for Asthma and Allergy - Wheaton

    Silver Spring, Maryland, 20902, United States

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100730, China

  • Penn State Milton S. Hershey MC - Penn State

    Hershey, Pennsylvania, 17033, United States

  • SP ZOZ Szpital Uniwersytecki w Krakowie

    Krakow, Lesser Poland Voivodeship, 31-066, Poland

  • The First Hospital of Lanzhou University

    Lanzhou, Gansu, 730000, China

  • Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei, 130030, China

  • Universitätsmedizin der Johannes Gutenberg

    Mainz, Rhineland-Palatinate, 55101, Germany

  • Washington University School of Medicine

    St Louis, Missouri, 63141, United States

  • West China Hospital, Sichuan University

    Chengdu, Sichaun, 610041, China

  • Yantai Yuhuangding Hospital

    Yantai, Shandong, 264000, China

Conditions

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