New brain cancer therapy BRiTE enters first human trial

NCT ID NCT04903795

First seen Nov 03, 2025 · Last updated May 02, 2026 · Updated 23 times

Summary

This early-stage study tests a new drug called BRiTE in 18 adults with a specific type of glioblastoma (EGFRvIII-positive). BRiTE is designed to help the body's immune T cells attack the tumor. It is given as a continuous 4-day IV infusion every 28 days. The main goal is to check safety and find the best dose.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.