New combo therapy aims to boost myeloma remission

NCT ID NCT07185477

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 21 times

Summary

This early-stage trial tests whether giving a bispecific antibody (GPRC5D/CD3) before CAR-T cell therapy can improve outcomes for adults with relapsed/refractory multiple myeloma, a blood cancer that has stopped responding to standard treatments. About 20 participants will receive the antibody first, then CAR-T cells, to see if this sequence leads to better tumor shrinkage and manageable side effects. The goal is to control the disease, not cure it, as ongoing management is still needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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