Can radiation and an antibiotic make CAR-T therapy safer and more effective?

NCT ID NCT07478848

First seen Mar 28, 2026 · Last updated May 13, 2026 · Updated 10 times

Summary

This early-stage trial tests whether giving radiation therapy and the antibiotic vancomycin before standard CAR-T cell treatment is safe and doable for people with large B-cell lymphoma. About 14 adults whose lymphoma has come back or not responded to treatment will take part. The goal is to see if this combination can reduce side effects and improve how well the cancer responds.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Abramson Cancer Center, University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.