New hope for rare skin lymphoma: drug after transplant may stop cancer return

NCT ID NCT07178457

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 35 times

Summary

This study tests whether giving brentuximab vedotin after a stem cell transplant can prevent early relapse in people with advanced cutaneous T-cell lymphoma (CTCL). About 84 adults aged 18-70 with CD30-positive mycosis fungoides who have had at least one prior treatment and are in remission after transplant will be randomly assigned to receive the drug or a placebo. The goal is to see if this approach improves progression-free survival compared to waiting until relapse occurs.

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