Oral pill challenges injection in fight against tough breast cancer

NCT ID NCT03781063

Completed Disease control Sponsor: Sermonix Pharmaceuticals Inc. Source: ClinicalTrials.gov ↗

Summary

This study tested whether an oral pill called lasofoxifene could work as well as or better than the standard injection (fulvestrant) for women with a specific type of advanced breast cancer. It focused on women whose cancer had stopped responding to other hormone therapies and had developed a particular genetic change (ESR1 mutation). The main goal was to see which treatment could keep the cancer from growing for a longer time.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED OR METASTATIC BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Beacon Health (JIT)

South Bend, Indiana, 46601, United States
CIUSSS de Saguenay-Lac-Saint Jean

Chicoutimi, Quebec, G7H5H6, Canada
Carle Cancer Center

Urbana, Illinois, 61801, United States
City of Hope Comprehensive Cancer

Duarte, California, 91010, United States
Compassionate Care Research Group

Fountain Valley, California, 92708, United States
Comprehensive Cancer Centers of Nevada (JIT)

Las Vegas, Nevada, 89128, United States
Duke University Medical Center

Durham, North Carolina, 27710, United States
Emory University

Atlanta, Georgia, 30322, United States
FMH James M Stockman Cancer Institute (JIT)

Frederick, Maryland, 21702, United States
Florida Cancer Specialists

Tallahassee, Florida, 32308, United States
HCA Midwest Health

Kansas City, Missouri, 64132, United States
Hadassah Ein Kerem Medical Center

Jerusalem, Israel, 9112001, Israel
Hattiesburg Clinic Hematology/Oncology

Hattiesburg, Mississippi, 39401, United States
Hawaii Cancer Care (JIT)

Honolulu, Hawaii, 96813, United States
Illinois Cancer Care (JIT)

Peoria, Illinois, 61615, United States
Jewish General Hospital

Montreal, Quebec, H3T1E2, Canada
Mary Crowley Cancer Research (JIT)

Dallas, Texas, 75230, United States
Mayo Clinic

Rochester, Minnesota, 55902, United States
Mayo Clinic Arizona

Phoenix, Arizona, 85054, United States
Mayo Clinic Florida

Jacksonville, Florida, 32224, United States
McGill University Health Centre

Montreal, Quebec, H4A3J1, Canada
Miami Cancer Institute

Miami, Florida, 33176, United States
New Jersey Cancer Care and Blood Disorders (JIT)

Belleville, New Jersey, 07203, United States
Ocala Oncology Center (JIT)

Oscala, Florida, 34474, United States
Ohio Health (JIT)

Columbus, Ohio, 43221, United States
Oncology Consultants (JIT)

Houston, Texas, 77024, United States
Peninsula Cancer Institute

Newport News, Virginia, 23601, United States
Rabin Medical Center

Petah Tikva, Israel, 49100, Israel
Robert H. Lurie Comprehensive Cancer Center of Northwestern University

Chicago, Illinois, 60611, United States
Rocky Mountain Cancer Centers

Longmont, Colorado, 80501, United States
Roswell Park Comprehensive Cancer Center

Buffalo, New York, 14263, United States
Saint Luke's Cancer Institute

Kansas City, Missouri, 64111, United States
Sanford Cancer Center (JIT)

Sioux Falls, South Dakota, 57104, United States
Sheba Medical Center

Ramat Gan, Israel, 52656021, Israel
Soroka University Medical Center

Beersheba, Israel, 84101, Israel
Summit Medical Group (JIT)

Florham Park, New Jersey, 07932, United States
Sunnybrook Health Sciences Center

Toronto, Ontario, M4N3M5, Canada
Tennessee Oncology Chattanooga

Chattanooga, Tennessee, 37404, United States
Tennessee Oncology/SCRI

Nashville, Tennessee, 37203, United States
The Bond Clinic Cancer & Research Center.

Winter Haven, Florida, 33880, United States
The Ohio State University - Comprehensive Cancer Center

Columbus, Ohio, 43210, United States
The Ottawa Hospital

Ottawa, Ontario, K1H8L6, Canada
TriHealth Cancer Institute

Cincinnati, Ohio, 45220, United States
UCSF Cancer Center

San Francisco, California, 94115, United States
UPMC Hillman Cancer Center

Pittsburgh, Pennsylvania, 15232, United States
University of Chicago

Chicago, Illinois, 60637, United States
University of Louisville / James Graham Brown Cancer Center

Louisville, Kentucky, 40202, United States
Utah Cancer Specialists (JIT)

Salt Lake City, Utah, 84102, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
West Cancer Center

Germantown, Tennessee, 38138, United States
Yuma Regional Medical Center (JIT)

Yuma, Arizona, 85364, United States

Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED OR METASTATIC BREAST CANCER