Early trial tests new combo for Tough-to-Treat breast cancer

NCT ID NCT04288089

Summary

This early-stage study is testing the safety of combining two drugs, H3B-6545 and palbociclib, for women with advanced or metastatic breast cancer that is estrogen receptor-positive and HER2-negative. The main goal is to find the highest dose patients can tolerate without severe side effects. Researchers are also looking at how the drugs work in the body and if they help control the cancer.

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Contacts and locations

Locations

  • Comprehensive Cancer Centers of Nevada

    Las Vegas, Nevada, 89169, United States

  • Florida Cancer Specialists South - SCRI - PPDS

    Sarasota, Florida, 34232, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Royal Marsden NHS Foundation Trust

    London, United Kingdom

  • Royal Marsden NHS Foundation Trust

    Sutton, United Kingdom

  • Saint Luke's Cancer Institute

    Kansas City, Missouri, 64111, United States

  • Sarah Cannon Research Institute UK - SCRI

    London, United Kingdom

  • Tennessee Oncology, PLLC - SCRI - PPDS

    Nashville, Tennessee, 37203, United States

Conditions

Explore the condition pages connected to this study.