New drug combo tested in kids with aggressive brain tumors

NCT ID NCT05081180

Summary

This study is testing a two-drug combination (avelumab and lenvatinib) in children with aggressive brain tumors that have returned or progressed after prior treatment. The first part aims to find a safe dose, while the second part will see if the combination can slow tumor growth. It involves 17 children with specific types of high-grade central nervous system tumors.

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Contacts and locations

Locations

  • CHU Angers - Hôpital Hôtel Dieu - Service de Cancérologie Pédiatrique

    Angers, France

  • CHU Sainte-Justine

    Montreal, Canada

  • Hôpital de la Timone

    Marseille, France

  • Institut Curie - Centre de Lutte Contre le Cancer (CLCC) de Paris

    Paris, France

  • Seoul National University Hospital

    Seoul, South Korea

  • Severance Hospital, Yonsei University Health System

    Seoul, South Korea

  • The Hospital for Sick Children

    Toronto, Canada

  • Universitaetsklinikum Hamburg Eppendorf

    Hamburg, Germany

  • Universitaetsklinikum Muenster

    Münster, Germany

Conditions

Explore the condition pages connected to this study.