Major brain cancer trial tests Two-Punch treatment strategy

NCT ID NCT00978458

Ongoing Disease control Sponsor: Eastern Cooperative Oncology Group Source: ClinicalTrials.gov ↗

Summary

This large study aims to find out if adding the chemotherapy drug temozolomide to standard radiation therapy works better for controlling low-grade brain tumors. It will enroll 540 adults whose tumors are causing symptoms or growing. The main goals are to see which approach keeps the cancer from progressing longer and helps patients live longer, while also tracking side effects and quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Arizona Oncology Services Foundation

Phoenix, Arizona, 85013, United States
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210-1240, United States
Aurora Presbyterian Hospital

Aurora, Colorado, 80012, United States
Barberton Citizens Hospital

Barberton, Ohio, 44203, United States
Billings Clinic - Downtown

Billings, Montana, 59107-7000, United States
BroMenn Regional Medical Center

Normal, Illinois, 61761, United States
CCOP - Christiana Care Health Services

Newark, Delaware, 19713, United States
CCOP - Colorado Cancer Research Program

Denver, Colorado, 80222, United States
CCOP - Duluth

Duluth, Minnesota, 55805, United States
CCOP - Greenville

Greenville, South Carolina, 29615, United States
CCOP - Illinois Oncology Research Association

Peoria, Illinois, 61615, United States
CCOP - Iowa Oncology Research Association

Des Moines, Iowa, 50309, United States
CCOP - Metro-Minnesota

Saint Louis Park, Minnesota, 55416, United States
CCOP - Missouri Valley Cancer Consortium

Omaha, Nebraska, 68106, United States
CCOP - Northern Indiana CR Consortium

South Bend, Indiana, 46601, United States
CCOP - Upstate Carolina

Spartanburg, South Carolina, 29303, United States
CCOP - Virginia Mason Research Center

Seattle, Washington, 98101, United States
CCOP - Wichita

Wichita, Kansas, 67214, United States
Cancer Center of Kansas, PA - Wellington

Wellington, Kansas, 67152, United States
Cancer Center of Kansas, PA - Wichita

Wichita, Kansas, 67214, United States
Cancer Center of Kansas, PA - Winfield

Winfield, Kansas, 67156, United States
Cancer Centers of the Carolinas - Eastside

Greenville, South Carolina, 29615, United States
Cancer Centers of the Carolinas - Faris Road

Greenville, South Carolina, 29605, United States
Cancer Centers of the Carolinas - Greer Medical Oncology

Greer, South Carolina, 29650, United States
Cancer Centers of the Carolinas - Greer Radiation Oncology

Greer, South Carolina, 29650, United States
Cancer Centers of the Carolinas - Grove Commons

Greenville, South Carolina, 29605, United States
Cancer Centers of the Carolinas - Seneca

Seneca, South Carolina, 29672, United States
Cancer Centers of the Carolinas - Spartanburg

Spartanburg, South Carolina, 29307, United States
Cancer Resource Center - Lincoln

Lincoln, Nebraska, 68510, United States
Cancer Treatment Center at Pekin Hospital

Pekin, Illinois, 61554, United States
Case Comprehensive Cancer Center

Cleveland, Ohio, 44106-5065, United States
Center for Cancer Therapy at LaPorte Hospital and Health Services

La Porte, Indiana, 46350, United States
Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center

Orange, California, 92868, United States
Charles M. Barrett Cancer Center at University Hospital

Cincinnati, Ohio, 45267, United States
Cleveland Clinic Taussig Cancer Center

Cleveland, Ohio, 44195, United States
Columbia Saint Mary's Hospital - Ozaukee

Mequon, Wisconsin, 53097, United States
Columbia-Saint Mary's Cancer Care Center

Milwaukee, Wisconsin, 53211, United States
Community Cancer Center

Normal, Illinois, 61761, United States
Community Hospital of Ottawa

Ottawa, Illinois, 61350, United States
Community Regional Cancer Care at Community Hospital East

Indianapolis, Indiana, 46219, United States
Community Regional Cancer Care at Community Hospital North

Indianapolis, Indiana, 46256, United States
Decatur Memorial Hospital Cancer Care Institute

Decatur, Illinois, 62526, United States
Diagnostic and Treatment Center

Weston, Wisconsin, 54476, United States
Dixie Regional Medical Center - East Campus

St. George, Utah, 84770, United States
Eastern Connecticut Hematology and Oncology Associates

Norwich, Connecticut, 06360, United States
Elkhart General Hospital

Elkhart, Indiana, 46515, United States
Eureka Community Hospital

Eureka, Illinois, 61530, United States
Evanston Hospital

Evanston, Illinois, 60201-1781, United States
Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States
Fairview Southdale Hospital

Edina, Minnesota, 55435, United States
Florida Hospital Cancer Institute at Florida Hospital Orlando

Orlando, Florida, 32803-1273, United States
Galesburg Clinic, PC

Galesburg, Illinois, 61401, United States
Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States
Gibbs Regional Cancer Center at Spartanburg Regional Medical Center

Spartanburg, South Carolina, 29303, United States
Graham Hospital

Canton, Illinois, 61520, United States
Gundersen Lutheran Center for Cancer and Blood

La Crosse, Wisconsin, 54601, United States
HealthEast Cancer Care at St. John's Hospital

Maplewood, Minnesota, 55109, United States
Hennepin County Medical Center - Minneapolis

Minneapolis, Minnesota, 55415, United States
Hollings Cancer Center at Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Howard Community Hospital

Kokomo, Indiana, 46904, United States
Humphrey Cancer Center at North Memorial Outpatient Center

Robbinsdale, Minnesota, 55422-2900, United States
Hurley Medical Center

Flint, Michigan, 48503, United States
Hutchinson Area Health Care

Hutchinson, Minnesota, 55350, United States
Illinois CancerCare - Bloomington

Bloomington, Illinois, 61701, United States
Illinois CancerCare - Canton

Canton, Illinois, 61520, United States
Illinois CancerCare - Carthage

Carthage, Illinois, 62321, United States
Illinois CancerCare - Community Cancer Center

Normal, Illinois, 61761, United States
Illinois CancerCare - Eureka

Eureka, Illinois, 61530, United States
Illinois CancerCare - Havana

Havana, Illinois, 62644, United States
Illinois CancerCare - Kewanee Clinic

Kewanee, Illinois, 61443, United States
Illinois CancerCare - Macomb

Macomb, Illinois, 61455, United States
Illinois CancerCare - Monmouth

Monmouth, Illinois, 61462, United States
Illinois CancerCare - Pekin

Pekin, Illinois, 61603, United States
Illinois CancerCare - Peru

Peru, Illinois, 61354, United States
Illinois CancerCare - Princeton

Princeton, Illinois, 61356, United States
Illinois CancerCare - Spring Valley

Spring Valley, Illinois, 61362, United States
Illinois Valley Community Hospital

Peru, Illinois, 61354, United States
John H. Stroger, Jr. Hospital of Cook County

Chicago, Illinois, 60612-3785, United States
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center

Murray, Utah, 84157, United States
Josephine Ford Cancer Center at Henry Ford Hospital

Detroit, Michigan, 48202, United States
Kimmel Cancer Center at Thomas Jefferson University - Philadelphia

Philadelphia, Pennsylvania, 19107-5541, United States
La Grange Memorial Hospital

La Grange, Illinois, 60525, United States
Lakeland Regional Cancer Care Center - St. Joseph

Saint Joseph, Michigan, 49085, United States
Lakeside Cancer Specialists, PLLC

Saint Joseph, Michigan, 49085, United States
Lakeview Hospital

Stillwater, Minnesota, 55082, United States
Legacy Good Samaritan Hospital & Comprehensive Cancer Center

Portland, Oregon, 97210, United States
Legacy Mount Hood Medical Center

Gresham, Oregon, 97030, United States
Legacy Salmon Creek Medical Center

Vancouver, Washington, 98686, United States
Louisville Oncology at Norton Cancer Institute - Louisville

Louisville, Kentucky, 40202, United States
M. D. Anderson Cancer Center at University of Texas

Houston, Texas, 77030-4009, United States
Maine Center for Cancer Medicine and Blood Disorders - Scarborough

Scarborough, Maine, 04074, United States
Marshfield Clinic - Indianhead Center

Rice Lake, Wisconsin, 54868, United States
Marshfield Clinic - Lakeland Center

Minocqua, Wisconsin, 54548, United States
Marshfield Clinic - Marshfield Center

Marshfield, Wisconsin, 54449, United States
Marshfield Clinic - Weston Center

Weston, Wisconsin, 54476, United States
Marshfield Clinic Cancer Care at Regional Cancer Center

Eau Claire, Wisconsin, 54701, United States
Marshfield Clinic at Saint Michael's Hospital

Stevens Point, Wisconsin, 54481, United States
Mayo Clinic - Jacksonville

Jacksonville, Florida, 32224, United States
Mayo Clinic Cancer Center

Rochester, Minnesota, 55905, United States
McDonough District Hospital

Macomb, Illinois, 61455, United States
Medical College of Wisconsin Cancer Center

Milwaukee, Wisconsin, 53226, United States
Memorial Hospital

Carthage, Illinois, 62321, United States
Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States
Memorial Sloan-Kettering Cancer Center

New York, New York, 10065, United States
Mercy Cancer Center at Mercy Medical Center - North Iowa

Mason City, Iowa, 50401, United States
Mercy and Unity Cancer Center at Mercy Hospital

Coon Rapids, Minnesota, 55433, United States
Mercy and Unity Cancer Center at Unity Hospital

Fridley, Minnesota, 55432, United States
Methodist Estabrook Cancer Center

Omaha, Nebraska, 68114, United States
Methodist Medical Center of Illinois

Peoria, Illinois, 61636, United States
Michiana Hematology-Oncology, PC - South Bend

Mishawaka, Indiana, 46545-1470, United States
Ministry Medical Group at Saint Mary's Hospital

Rhinelander, Wisconsin, 54501, United States
Minnesota Oncology - Maplewood

Maplewood, Minnesota, 55109, United States
Minnesota Oncology - Woodbury

Woodbury, Minnesota, 55125, United States
Mission Hospitals - Memorial Campus

Asheville, North Carolina, 28801, United States
Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest

Allentown, Pennsylvania, 18105, United States
Nebraska Medical Center

Omaha, Nebraska, 68198, United States
New York Oncology Hematology, PC at Albany Medical Center

Albany, New York, 12208, United States
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, 03756-0002, United States
Norton Suburban Hospital

Louisville, Kentucky, 40207, United States
OSF Holy Family Medical Center

Monmouth, Illinois, 61462, United States
OSF St. Francis Medical Center

Peoria, Illinois, 61615-7827, United States
Oncology Hematology Associates of Central Illinois, PC - Ottawa

Ottawa, Illinois, 61350, United States
Oncology Hematology Associates of Central Illinois, PC - Peoria

Peoria, Illinois, 61615, United States
Park Nicollet Cancer Center

Saint Louis Park, Minnesota, 55416, United States
Parkview Regional Cancer Center at Parkview Health

Fort Wayne, Indiana, 46805, United States
Porter Adventist Hospital

Denver, Colorado, 80210, United States
Presbyterian - St. Luke's Medical Center

Denver, Colorado, 80218, United States
Proctor Hospital

Peoria, Illinois, 61614, United States
Radiation Oncology Associates Southwest

Fort Wayne, Indiana, 46804, United States
Rapid City Regional Hospital

Rapid City, South Dakota, 57701, United States
Rebecca and John Moores UCSD Cancer Center

La Jolla, California, 92093-0658, United States
Regions Hospital Cancer Care Center

Saint Paul, Minnesota, 55101, United States
Ridgeview Medical Center

Waconia, Minnesota, 55387, United States
Robert H. Lurie Comprehensive Cancer Center at Northwestern University

Chicago, Illinois, 60611-3013, United States
SUNY Upstate Medical University Hospital

Syracuse, New York, 13210, United States
Saint Joseph's Hospital

Marshfield, Wisconsin, 54449, United States
Sanford Cancer Center at Sanford USD Medical Center

Sioux Falls, South Dakota, 57117-5039, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Baltimore, Maryland, 21231-2410, United States
Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas

Dallas, Texas, 75390, United States
Siouxland Hematology-Oncology Associates, LLP

Sioux City, Iowa, 51101, United States
Sky Ridge Medical Center

Lone Tree, Colorado, 80124, United States
St. Anthony Central Hospital

Denver, Colorado, 80204, United States
St. Francis Cancer Center at St. Francis Medical Center

Shakopee, Minnesota, 55379, United States
St. Joseph Hospital

Denver, Colorado, 80218, United States
St. Joseph Medical Center

Bloomington, Illinois, 61701, United States
St. Luke's Cancer Network at St. Luke's Hospital

Bethlehem, Pennsylvania, 18015, United States
St. Vincent Hospital Regional Cancer Center

Green Bay, Wisconsin, 54307-3508, United States
Summa Center for Cancer Care at Akron City Hospital

Akron, Ohio, 44309-2090, United States
Swedish Medical Center

Englewood, Colorado, 80110, United States
Theda Care Cancer Institute

Appleton, Wisconsin, 54911, United States
UAB Comprehensive Cancer Center

Birmingham, Alabama, 35294, United States
United Hospital

Saint Paul, Minnesota, 55102, United States
University Cancer Center at University of Washington Medical Center

Seattle, Washington, 98195, United States
University of Chicago Cancer Research Center

Chicago, Illinois, 60637-1470, United States
University of Illinois Cancer Center

Chicago, Illinois, 60612-7243, United States
University of Texas Medical Branch

Galveston, Texas, 77555-0361, United States
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center

Madison, Wisconsin, 53792-6164, United States
Utah Valley Regional Medical Center - Provo

Provo, Utah, 84604, United States
Valley Cancer Center

Spring Valley, Illinois, 61362, United States
Vanderbilt-Ingram Cancer Center

Nashville, Tennessee, 37232-6838, United States
Via Christi Cancer Center at Via Christi Regional Medical Center

Wichita, Kansas, 67214, United States
Virginia Commonwealth University Massey Cancer Center

Richmond, Virginia, 23298-0037, United States
Virginia Piper Cancer Institute at Abbott - Northwestern Hospital

Minneapolis, Minnesota, 55407, United States
Wake Forest University Comprehensive Cancer Center

Winston-Salem, North Carolina, 27157-1096, United States
Waukesha Memorial Hospital Regional Cancer Center

Waukesha, Wisconsin, 53188, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007-3731, United States
Willmar Cancer Center at Rice Memorial Hospital

Willmar, Minnesota, 56201, United States
Winship Cancer Institute of Emory University

Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.

BRAIN AND CENTRAL NERVOUS SYSTEM TUMORS NEUROTOXICITY