New hope for brain cancer patients in groundbreaking UK drug trial

NCT ID NCT06630260

Summary

This UK trial is testing new oral drug combinations for aggressive brain tumors like glioblastoma. It aims to see if the drugs avutometinib and defactinib, given alone or with a standard chemotherapy, are safe and can help control tumor growth. The study will enroll 182 patients whose tumors have specific genetic markers, first testing in people whose cancer has returned, then potentially in newly diagnosed patients.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cambridge University Hospitals

    RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Royal Marsden Hospital - Drug Development Unit

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Royal Marsden Hospital - Neuro-Oncology Unit

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.