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Magnetic pulses to the brain target gambling cravings

NCT ID NCT07828782

Symptom relief Sponsor: Sveti Ivan Psychiatric Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

Researchers at Sveti Ivan Psychiatric Hospital are testing whether high-frequency repetitive transcranial magnetic stimulation (rTMS) with the H7 coil reduces gambling disorder symptoms. The trial enrolls 60 men aged 18 to 64 who are starting treatment at a gambling disorder day hospital. Participants are randomly assigned to active rTMS or a sham treatment that feels similar but delivers no active magnetic stimulation, and neither they nor the assessors know which they receive. Everyone continues their usual care. Over six weeks, the team measures changes in gambling symptom severity, cravings, heart rate variability, and cost, and looks for personal or clinical traits that predict who responds.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation using the H7 coil
What this could lead to
If it works, deep brain stimulation with the H7 coil could offer a non-drug option for people whose gambling disorder has not responded to standard care.
What could go wrong
This is a small, six-week study of 60 men, so any benefit may be short-lived or may not apply to women or to people with other conditions. Brain stimulation can cause scalp discomfort, headache, or lightheadedness, and the sham comparison means some participants receive no active magnetic pulses.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 64 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * confirmed GD diagnosis according to ICD-10 (F63.0) * age between 18 and 64 years * male gender * enrolled in GD treatment at the GD-DH of the UPC Sveti Ivan within two weeks of study inclusion. * right-hand dominance Exclusion Criteria: * diagnosis of a schizophrenia spectrum disorder (ICD-10, F20-F29) * diagnosed psychotic episode within six months prior to inclusion * current suicidality * clinically relevant neurological disorder or history of cerebrovascular insult * diagnosis of a mental and behavioral disorder due to the use of psychoactive substances (ICD-10, F10-F19) (except nicotine dependence) * diagnosed moderate or severe dementia * presence of intracranial implants * inability to independently complete questionnaires * refusal to participate due to discomfort during DLPFC localization

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Conditions

The condition(s) this trial relates to.

pathological gambling

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gambling disorder

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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