New hope for controlling breast cancer brain spread

NCT ID NCT05041842

Summary

This study is testing whether adding the drug tucatinib to standard treatments can better control breast cancer that has spread to the brain. It involves 53 adults with HER2-positive metastatic breast cancer whose cancer progressed in the brain but is stable elsewhere in the body. The goal is to see if this three-drug combination can delay cancer progression and improve survival after patients receive local brain treatment like radiation or surgery.

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Contacts and locations

Locations

  • CARIO - Centre Armoricain Radiothérapie Imagerie Médicale et Oncologi

    Plérin, France

  • Centre Antoine Lacassagne

    Nice, France

  • Centre Francois Baclesse

    Caen, France

  • Centre Georges François Leclerc

    Dijon, France

  • Centre Henri Becquerel

    Rouen, France

  • Centre Hospitalier Annecy Genevois

    Pringy, France

  • Centre Hospitalier Universitaire de Tours

    Tours, France

  • Centre Leon Berard

    Lyon, France

  • Clinique Victor Hugo

    Le Mans, 72000, France

  • Gustave Roussy

    Villejuif, France

  • Hôpital privé Jean Mermoz

    Lyon, France

  • Institut Bergonié

    Bordeaux, France

  • Institut Claudius Regaud

    Toulouse, France

  • Institut Jean Godinot

    Reims, France

  • Institut de Cancérologie de l'Ouest - Site Paul Papin

    Angers, France

  • Institut du cancer de Montpellier

    Montpellier, 34090, France

Conditions

Explore the condition pages connected to this study.