Fluorescent dye reveals hidden brain drains in cadavers
NCT ID NCT07682155
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study investigates how fluid drains from the brain to lymph nodes in the neck, a connection that may be important for clearing waste linked to Alzheimer's disease. Researchers will inject a fluorescent dye into the meningeal space of recently deceased organ donors and track its movement with a special camera. The goal is to map the drainage pathways and identify which neck lymph nodes are involved, providing insights that could guide future treatments for neurological disorders.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- indocyanine green
- What this could lead to
- If this study maps the brain's drainage pathways clearly, it could help researchers develop better treatments for Alzheimer's and other brain disorders.
- What could go wrong
- This is a very small, early-stage study in cadavers, so findings may not fully apply to living humans. The dye may not migrate as expected, limiting what can be learned.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Germans Trias i Pujol Universitary Hospital
RECRUITINGBadalona, Barcelona, 08916, Spain