Fluorescent dye reveals hidden brain drains in cadavers

NCT ID NCT07682155

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study investigates how fluid drains from the brain to lymph nodes in the neck, a connection that may be important for clearing waste linked to Alzheimer's disease. Researchers will inject a fluorescent dye into the meningeal space of recently deceased organ donors and track its movement with a special camera. The goal is to map the drainage pathways and identify which neck lymph nodes are involved, providing insights that could guide future treatments for neurological disorders.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

indocyanine green

What this could lead to

If this study maps the brain's drainage pathways clearly, it could help researchers develop better treatments for Alzheimer's and other brain disorders.

What could go wrong

This is a very small, early-stage study in cadavers, so findings may not fully apply to living humans. The dye may not migrate as expected, limiting what can be learned.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Germans Trias i Pujol Universitary Hospital

    RECRUITING

    Badalona, Barcelona, 08916, Spain