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Brain scans and blood tests could predict timing of death for organ donation

NCT ID NCT07698262

Knowledge-focused Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Aug 21, 2026 · Updated 2 times

Summary

This study aims to develop a tool that uses brain biomarkers, CT scans, and heart rate data to predict how quickly a patient will die after life support is withdrawn. The goal is to improve planning for organ donation and give families and healthcare teams more accurate information. Researchers will enroll 102 adults who are eligible for donation after circulatory death.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this tool could help doctors and families know sooner whether organ donation is possible, improving donation rates and giving families clearer information.
What could go wrong
This is an early-stage study with 102 participants, so the tool may not be accurate enough for widespread use. It also only applies to patients already eligible for donation after circulatory death.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 102 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jan 2027

An estimate. Start dates often move.

Expected to finish

Dec 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

ICU

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥ 19; 2. Eligible for DCD Exclusion Criteria: 1. Complete high cervical spinal cord injury (C5 and above) 2. Pacemaker in situ 3. Tracheostomy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Organ donation after circulatory death

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    11 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Children's Hospital of Eastern Ontario (CHEO)

    Ottawa, Ontario, Canada

  • Cumming School of Medicine

    Calgary, Alberta, Canada

  • Kelowna General Hospital

    Kelowna, British Columbia, Canada

  • Lakeridge Health

    Oshawa, Ontario, L1G 8A2, Canada

  • Royal Columbian Hospital

    New Westminster, British Columbia, Canada

  • St Paul hospital

    Vancouver, Canada

  • Surrey Memorial Hospital

    Surrey, British Columbia, Canada

  • UBC/East Kootenay Regional Hospital

    Cranbrook, British Columbia, Canada

  • University Hospital - London Health Sciences Centre

    London, Ontario, N6A 3K7, Canada

  • University of Manitoba Health Sciences Center

    Winnipeg, Manitoba, Canada

  • Vancouver General Hospital

    Vancouver, British Columbia, V5Z1M9, Canada