Researchers examine current treatments for aggressive colorectal cancer

NCT ID NCT04317599

Completed Knowledge-focused Sponsor: Pierre Fabre Medicament Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked back at medical records of 274 people with a specific type of advanced colorectal cancer (BRAF V600E mutation) to see what treatments they received and how well they worked. The goal was to understand real-world treatment patterns and outcomes, since there is no standard targeted therapy for this group. The study did not test new treatments but gathered information to help guide future research and healthcare decisions.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAF V600E MUTATION POSITIVE METASTATIC COLORECTAL CANCER

Contacts and locations

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Locations

AUSL-IRCCS of Reggio Emilia-Clinical Cancer Center

Reggio Emilia, Italy
AZ Klina

Brasschaat, Belgium
Asst Valle Olona

Saronno, Italy
Azienda Ospedaliero-Universitaria Pisana

Pisa, Italy
Barmherzige Brüder Krankenhaus St. Veit/Glan.

Saint Veit/Glan, Austria
CHC MontLégia

Liège, Belgium
CHRU de Besançon

Besançon, France
CHU Grenoble Alpes

La Tronche, France
CHU de Poitiers

Poitiers, France
Centre Oscar Lambert

Lille, France
Clinica Oncologica Ospedali Riuniti di Ancona

Ancona, Italy
Facharztzentrum Eppendorf

Hamburg, Germany
GHPSO (Groupe Hospitalier Sud de l'Oise)

Creil, France
Gustave Roussy

Villejuif, France
Harrogate & District NHS Foundation Trust

Harrogate, United Kingdom
Hospital General Universitario de Valencia

Valencia, Spain
Hospital del Mar

Barcelona, Spain
Hôpital Franco-Britannique

Levallois-Perret, France
ICM Val d'Aurelle

Montpellier, France
Imelda VZW

Bonheiden, Belgium
Imperial College Healthcare NHS Trust

London, United Kingdom
Instituto Nazionale Tumori, IRCCS, Fondazione G. Pascale

Naples, Italy
Klinikum Aschaffenburg Medical Klinik IV

Aschaffenburg, Germany
La Paz University Hospital

Madrid, Spain
MVZ Mitte Leipzig

Leipzig, Germany
MZ Onkologie Velbert/Ratingen/Mettmann

Velbert, Germany
Medizinische Universität Wien

Vienna, Austria
Oncoresearch Lerchenfeld

Hamburg, Germany
Santa Maria Goretti Hospital

Latina, Italy
Studienzentrale Gokos

Dresden, Germany
UZ Leuven

Leuven, Belgium
University College London Hospitals NHS Foundation Trust

London, United Kingdom
University Hospitals Birmingham NHS Foundation Trust

Birmingham, United Kingdom
Universitätsklinikum Essen

Essen, Germany

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