New hope for chinese patients with hard-to-treat colorectal cancer

NCT ID NCT05004350

First seen May 04, 2026 · Last updated May 16, 2026 · Updated 4 times

Summary

This study tested a new combination of drugs (encorafenib and cetuximab) against standard treatments in 107 Chinese patients with a specific genetic mutation (BRAF V600E) causing metastatic colorectal cancer. The goal was to see if the new combo could slow cancer growth better than current options. Participants received either the new combo or standard chemotherapy, and researchers measured how long the cancer stayed under control.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100036, China

  • Cancer Center of Guangzhou Medical University

    Guangzhou, Guangdong, 510095, China

  • Cancer Hospital Affiliated to Shantou University Medical College

    Shantou, Guangdong, 515041, China

  • First Affiliated Hospital of Gannan Medical University

    Ganzhou, Jiangxi, 341001, China

  • Fujian Medical University - Fujian Provincial Cancer Hospital

    Fuzhou, Fujian, 350014, China

  • Harbin Medical University Cancer Hospital

    Harbin, Heilongjiang, 150040, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450008, China

  • Huashan Hospital Fudan University

    Shanghai, Shanghai Municipality, 200040, China

  • Liaoning Cancer Hospital & Institute

    Shenyang, Liaoning, 110042, China

  • Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

    Beijing, Beijing Municipality, 100730, China

  • Peking University Shenzhen Hospital

    Shenzhen, Guangdong, 518036, China

  • Shaanxi Provincial People's Hospital

    Xi'an, Shaanxi, 710068, China

  • Shanghai East Hospital, Tongji University

    Shanghai, Shanghai Municipality, 200120, China

  • Sir Run Run Shaw Hospital - Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310016, China

  • The Affiliated Hospital of Hebei University

    Baoding, Hebei, 071000, China

  • The First Affiliated Hospital - Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310003, China

  • The First Affiliated Hospital of Jinzhou Medical University

    Jinzhou, Liaoning, 121011, China

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, 330006, China

  • The First Affiliated Hospital of Xiamen University

    Xiamen, Fujian, 361001, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

  • The First Hospital of China Medical University

    Shenyang, Liaoning, 110001, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The First People's Hospital of Changzhou

    Changzhou, Jiangsu, 213003, China

  • The First People's Hospital of Foshan

    Foshan, Guangdong, 528010, China

  • The Second Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, 330006, China

  • The Second People's Hospital of Neijiang

    Neijiang, Sichuan, 641000, China

  • The Sixth Affiliated Hospital Sun Yat-Sen University

    Guangzhou, Guangdong, 510655, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Tianjin Municipality, 300060, China

  • Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei, 430030, China

  • Union Hospital Tongji medical college Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

  • Xiangya Hospital Central South University

    Changsha, Hunan, 410008, China

  • Xinhua Hospital Affilliated to Shanghai Jiaotong University School of Medicine

    Shanghai, Shanghai Municipality, 200092, China

  • Zhongnan Hospital of Wuhan University

    Wuhan, Hubei, 430071, China

  • Zhongshan Hospital Fudan University

    Shanghai, Shanghai Municipality, 200032, China

Conditions

Explore the condition pages connected to this study.