New drug duo tested in fight against rare, aggressive blood cancer

NCT ID NCT07007052

Summary

This study is testing whether combining two drugs, tagraxofusp and venetoclax, is safe and effective for adults newly diagnosed with a rare and aggressive blood cancer called BPDCN. The main goal is to see if this combination leads to a complete remission after three months of treatment. Participants will receive at least three cycles of the drugs, and their response will determine if they continue treatment, receive a stem cell transplant, or stop therapy.

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Contacts and locations

Locations

  • AMIENS - CH Amiens Picardie Site Sud

    Amiens, 80054, France

  • ANGERS - CHU - Maladies du sang

    Angers, 49933, France

  • AP-HP - Hôpital Necker

    Paris, 75015, France

  • AP-HP- CRETEIL - CHU Henri Mondor

    Créteil, 94000, France

  • APHP - HOPITAL COCHIN - Hématologie

    Paris, 75014, France

  • APHP - Hôpital Saint-Louis - Hématologie adultes

    Paris, 75010, France

  • ARGENTEUIL - Centre hospitalier Victor Dupouy

    Argenteuil, France

  • AVIGNON - Centre Hospitalier

    Avignon, 84000, France

  • BESANCON - Hôpital Jean Minjoz - Hématologie

    Besançon, 25030, France

  • BORDEAUX - Hôpital Haut-Levêque

    Pessac, 33600, France

  • CHU SAINT-ETIENNE - iCHUSE

    Saint-Etienne, 42271, France

  • CLAMART - Hôpital d'Instruction des Armées de Percy

    Clamart, 92140, France

  • Clermont-Ferrand - Chu Estaing

    Clermont-Ferrand, 63000, France

  • Corbeil-Essonnes - Ch Sud Francilien

    Corbeil-Essonnes, France

  • Grenoble CHU - Hématologie Clinique

    Grenoble, 38043, France

  • LILLE CHU - Hôpital Claude Huriez

    Lille, 59037, France

  • LYON HCL- Site Sud

    Lyon, France

  • Limoges CHU

    Limoges, France

  • MARSEILLE - Institut Paoli-Calmettes

    Marseille, 13000, France

  • METZ - CHR Metz-Thionville

    Metz, 57085, France

  • MULHOUSE GHRMSA - Hôpital E. Muller - Hématologie

    Mulhouse, 68070, France

  • Montpellier - Chu Saint Eloi

    Montpellier, France

  • NANCY - CHU de Brabois

    Vandœuvre-lès-Nancy, 54500, France

  • NANTES - Hôpital Hôtel Dieu - Hématologie Clinique

    Nantes, 44093, France

  • Nimes CHU

    Nîmes, France

  • POITIERS - Hôpital La Milétrie - Hématologie Clinique

    Poitiers, 86000, France

  • REIMS - Hôpital Robert Debré - Hématologie Clinique

    Reims, 51100, France

  • RENNES - CHU Pontchaillou - Hématologie Clinique

    Rennes, 35033, France

  • ROUEN - Centre Henri Becquerel - Service Hématologie Clinique

    Rouen, 76038, France

  • Strasbourg - Institut de Cancerologie Strasbourg

    Strasbourg, 67200, France

  • TOURS - Hôpital Bretonneau

    Tours, 37000, France

  • Toulouse - IUCT Oncopole - Service d'Hématologie

    Toulouse, France

  • VERSAILLES - Hôpital André Mignot

    Versailles, France

  • Villejuif Igr - Gustave Roussy

    Villejuif, 94804, France

Conditions

Explore the condition pages connected to this study.