Botox vs. painkiller: which eases muscle pain better?

NCT ID NCT06899438

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested whether botulinum toxin type-A injections relieve pain from myofascial pain syndrome better than a standard local anesthetic (prilocaine). Thirty-eight adults with long-term muscle pain were randomly assigned to receive either botulinum toxin or prilocaine injections into their trigger points. Pain levels were measured before treatment and at 2 and 6 weeks after using standard pain scales.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
botulinum toxin type-A injection
What this could lead to
If it works, this could offer a longer-lasting pain relief option for people with myofascial pain syndrome.
What could go wrong
This is a small, completed trial with only 38 participants, so results may not apply to everyone. Botulinum toxin injections can cause temporary muscle weakness or bruising.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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