Botox injection may ease knee stiffness after ACL repair

NCT ID NCT05008731

First seen Jan 11, 2026 · Last updated Apr 24, 2026 · Updated 13 times

Summary

This study tests whether a single injection of botulinum toxin (Botox) into the hamstring muscle can reduce tightness and prevent a complication called cyclops syndrome after ACL knee surgery. About 132 adults who still have significant knee stiffness one month after their operation will receive either Botox or a placebo. The main goal is to see if more people in the Botox group can fully straighten their knee two months after the injection.

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Contacts and locations

Locations

  • Clinique du Sport

    Paris, 75005, France

Conditions

Explore the condition pages connected to this study.