Can Plant-Based mouthwash soothe gums and boost oral health?
NCT ID NCT07771907
First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time
Summary
This trial tests whether daily use of a botanical mouthwash for 14 days can improve gum health in healthy adults. Researchers compare two proprietary botanical blends, a combination of both, and a placebo rinse. They measure gum inflammation, dry mouth symptoms, and changes in the mouth's natural bacteria to see if these plant-based ingredients offer real benefits for everyday oral care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Botanical mouthwash (two proprietary botanical blends, tested separately and in combination)
- What this could lead to
- If successful, these botanical blends could become ingredients in everyday oral care products that help reduce gum inflammation and improve oral comfort.
- What could go wrong
- This is a small, short-term study in healthy adults, so results may not apply to people with gum disease. The botanicals may also cause allergic reactions or other side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy Adults Exclusion Criteria: * Women who are pregnant, breastfeeding, or planning to become pregnant during the study period * Known allergy or hypersensitivity to any of the study materials or ingredients * Current smokers or individuals who have used tobacco products (including smokeless tobacco) within the last 6 months * Antibiotic use within 3 months of study start * Current use of key drugs - Systemic Anti-inflammatory Drugs, Immunosuppressants, and Drugs known to cause Xerostomia * Current use of anti-gingivitis products Presence of extensive fixed or removable prosthodontic appliances or less than 50% of natural teeth * History of diagnosed periodontal disease requiring treatment, including active periodontal disease, extensive untreated caries, or significant oral lesions * History of chronic systemic diseases including: cardiovascular disease, uncontrolled diabetes, autoimmune diseases, HIV, and Hepatitis B or C * Concurrent participation in another clinical study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Advanced Imaging & Measurement Lab Access Business Group
Grand Rapids, Michigan, 49355, United States
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