New cocktail targets Hard-to-Treat cancers

NCT ID NCT00479128

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 35 times

Summary

This early-phase study tests a combination of three drugs—bortezomib, gemcitabine, and doxorubicin—in people with advanced urothelial cancer or other solid tumors that cannot be removed by surgery. The main goal is to find the safest dose of the two chemotherapy drugs when given with bortezomib. Researchers will also check if the tumors shrink. About 80 participants are enrolled at M.D. Anderson Cancer Center.

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Contacts and locations

Locations

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.