Morning sickness pill put to the test in pregnant teens

NCT ID NCT05289557

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether Bonjesta, a drug already used for morning sickness in adults, works and is safe for pregnant teenagers aged 12 to 17. About 274 teens will receive either Bonjesta or a placebo for 15 days. The goal is to see if it reduces nausea and vomiting better than a sugar pill.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bonjesta (doxylamine succinate and pyridoxine hydrochloride)

What this could lead to

If it works, this could provide a safe, effective option to ease morning sickness specifically for pregnant teens.

What could go wrong

The trial is currently suspended, so results are delayed. It's a small, short study (15 days) and may not show a clear benefit over placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Morning Sickness Nausea Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advances in Health

    Pearland, Texas, 77584, United States

  • Axon Clinical Research

    Mesquite, Texas, 75149, United States

  • Clinical Research Prime

    Idaho Falls, Idaho, 83404, United States

  • Clinovacare Medical Research Center

    West Columbia, South Carolina, 29169, United States

  • Emerald Coast OB/GYN Clinical Research

    Panama City, Florida, 32405, United States

  • Maximos OBGYN

    League City, Texas, 77573, United States

  • New Horizon Research Center

    Miami, Florida, 33165, United States

  • Unified Women's Clinical Research

    Winston-Salem, North Carolina, 27043, United States

  • Velvet Clinical Research

    Burbank, California, 91506, United States

  • Vital Pharma Research

    Hialeah, Florida, 33016, United States