Birth control pill vs. vaginal ring: which is better for your bones?

NCT ID NCT02367846

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study compares the effects of oral contraceptive pills and a contraceptive vaginal ring on bone turnover in young, exercising women aged 18-25. Using a special calcium tracer, researchers measure how each method changes bone calcium balance over 49 days. The goal is to understand whether the route of hormone delivery influences bone health, which could guide contraceptive choices for active women.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ethinyl estradiol (combined oral contraceptive and contraceptive vaginal ring)
What this could lead to
If it works, this could help women choose a contraceptive method that minimizes bone loss, especially for those at risk of osteoporosis.
What could go wrong
This is a very small early-phase study with only 6 participants, so results may not apply to all women. The intervention is short-term, and long-term bone effects remain unknown.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Women's Health and Exercise Laboratories, The Pennsylvania State University

    University Park, Pennsylvania, 16802, United States